Calcium accumulation in experimental hypertension

Tomera, John F.; Lilford, K.; Friend, Kevin D.; Kukulka, S.P.; Harakal, Concetta

doi:10.1016/0278-6915(95)00028-z

Cited by 5 publications

(1 citation statement)

References 17 publications

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“…In the history of the studies investigating the role of metals in vascular cells, calcium (Ca) was extensively examined compared to other metals using old techniques because Ca has essential roles in normal cardiovascular function and cardiovascular diseases including atherosclerosis (atherosclerotic vascular disease) and hypertension [28]. Importantly, vascular calcification is a prominent feature of atherosclerosis [29].…”

Section: Calcium and Vascular Cellsmentioning

confidence: 99%

Metallomics and Metal Effects in Vascular Systems

Hayashida¹

2015

Biochem Anal Biochem

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All living things cannot maintain their homeostasis or survive without metals. For example, the homeostasis of metal ions; iron (Fe), copper (Cu), zinc (Zn), manganese (Mn), potassium (K), sodium (Na), and calcium (Ca), is critical for many biological activities. On the other hand, the disorder of metal homeostasis leads to various human disorders including vascular system abnormalities. Metallomics is an analytic technology investigating the entirety of metals and metalloid species within a cell or tissues. Metallomics is an emerging field as well as metalloproteomics, however, the technological advances are very rapid and brings a lot of novel information. Metallomics consists of three main techniques; Atomic absorption spectrometry (AAS), Inductively coupled plasma (ICP), and X-ray fluorescence spectrometry (XRF). These novel techniques are recently applied to the studies of human diseases related to vascular system. Therefore, the significant information contributing to the development of novel therapy will be given us by metallomics in the near future.

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Section: Calcium and Vascular Cellsmentioning

confidence: 99%