Calcium‐ and potassium‐permeable plasma membrane transporters are activated by copper in <i>Arabidopsis</i> root tips: linking copper transport with cytosolic hydroxyl radical production

Rodrigo-Moreno, Ana; Andrés-Colás, Nuria; Poschenrieder, Charlotte; Gunsè, Benet; Peñarrubia, Lola; Shabala, Sergey

doi:10.1111/pce.12020

Cited by 75 publications

(36 citation statements)

References 51 publications

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“…Taking Cu as the exemplar, it plays a positive role in hydroxyl radical-activated cell wall loosening for root elongation (Fry et al, 2002) and this could be coupled in Arabidopsis roots to hydroxyl radical-activation of PM Annexin1-mediated Ca 2+ influx to stimulate exocytosis and growth (Foreman et al, 2003; Laohavisit et al, 2012). This model proposes regulation by extracellular hydroxyl radicals while Rodrigo-Moreno et al (2013) have proposed that Cu + binding at the intracellular face of the PM in Arabidopsis root tips catalyzes hydroxyl radical production to regulate ion flux. This would allow coupling of Cu transport into the root to regulation of PM Ca 2+ influx channels.…”

Section: Heavy Metal Stress Has the Capacity To Distort Ca2+ Signalingmentioning

confidence: 99%

Calcium-Mediated Abiotic Stress Signaling in Roots

et al. 2016

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Roots are subjected to a range of abiotic stresses as they forage for water and nutrients. Cytosolic free calcium is a common second messenger in the signaling of abiotic stress. In addition, roots take up calcium both as a nutrient and to stimulate exocytosis in growth. For calcium to fulfill its multiple roles must require strict spatio-temporal regulation of its uptake and efflux across the plasma membrane, its buffering in the cytosol and its sequestration or release from internal stores. This prompts the question of how specificity of signaling output can be achieved against the background of calcium’s other uses. Threats to agriculture such as salinity, water availability and hypoxia are signaled through calcium. Nutrient deficiency is also emerging as a stress that is signaled through cytosolic free calcium, with progress in potassium, nitrate and boron deficiency signaling now being made. Heavy metals have the capacity to trigger or modulate root calcium signaling depending on their dose and their capacity to catalyze production of hydroxyl radicals. Mechanical stress and cold stress can both trigger an increase in root cytosolic free calcium, with the possibility of membrane deformation playing a part in initiating the calcium signal. This review addresses progress in identifying the calcium transporting proteins (particularly channels such as annexins and cyclic nucleotide-gated channels) that effect stress-induced calcium increases in roots and explores links to reactive oxygen species, lipid signaling, and the unfolded protein response.

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Section: Heavy Metal Stress Has the Capacity To Distort Ca2+ Signalingmentioning

confidence: 99%

Calcium-Mediated Abiotic Stress Signaling in Roots

et al. 2016

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“…Non-essential elements (mainly Res) activate plant response genes, alter plasmatic membrane potential (Kenderesová et al, 2012), and induce ROS and Casignaling (Rodrigo-Moreno et al, 2013) in response to ion effects. The production of antioxidant defenses triggered by the presence of certain non-essential elements depends on the type and concentration of the element but also on the plant species (Rodríguez-Serrano et al, 2009).…”

Section: Towards a New Cocktail Of Necessary Nutrients (Cnn)mentioning

confidence: 99%

Integrating Plant Nutrients and Elicitors for Production of Secondary Metabolites, Sustainable Crop Production and Human Health: A Review

Luciano¹,

Irineo²,

Virginia³

et al. 2017

IJAB

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Plants are essential sources of bioactive substances that promote health. For economic reasons, farmers usually focus on obtaining higher yields rather than crop nutraceutical quality. The application of non-essential elements (NEEs) is a technique used to increase secondary metabolites (SMs) in plants. This technique includes variations of the essential elements ratios in a nutrient solution or the inclusion of elicitors, such as salicylic acid or methyl jasmonate. Elicitor use is controversial because plants grow differently in inert substrates, in vitro and soil. Soil contains essential elements (EEs) and NEEs that can enhance SM synthesis and increase nutraceutical plant quality. However, any technique that modifies plant metabolism can decrease yields. Thus, developing techniques to increase both agricultural product yield and quality is necessary. This review aims to demonstrate the necessity for a new recipe or "cocktail" of plant nutrients based on EEs and NEEs, and elicitors apply to achieve both a high yield and crops nutraceutical quality.

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“…The relevance of the COPT level in Cu uptake has been demonstrated in transgenic plants where COPT1 expression has been altered from overexpressing to complete loss. 10 We conclude from these studies that the regulation of the expression of the COPT transporters has a strong effect on the Cu concentrations inside cells.…”

Section: Plasma Membrane Copts and Copper Transportmentioning

confidence: 73%

“…9 Cu uptake depends on both its availability in the apoplast and the density of Cu transporter proteins at the plasma membrane. 10 Under deficiency, the predominant strategy for Cu acquisition consists in a mechanism of reduction of Cu 2C to Cu C and subsequent Cu C uptake. 11,12 Cu entrance is mostly dependent on the quantity of high affinity Cu transporters.…”

Section: Plasma Membrane Copts and Copper Transportmentioning

confidence: 99%