Calcium, Magnesium and Phosphorous Levels in Serum of Iraqi Women with Fibromyalgia

Abstract

Fibromyalgia (FM) is a common, debilitating, and chronic pain syndrome. The women are more likely to have more tender points on examination than are their male counterparts. Iraqi study showed that FM occur in 1.5% among adolescents of Iraqi population. In compare to normal healthy women, present study was revealed that Iraqi women with FM have significant elevation of calcium (p = 0.003) with significant reduction of magnesium (p = 0.001), whereas the inorganic phosphorous was not differs (p = 0.31). In conclusion, magnesium and calcium would play a crucial role in etiopathogenesis of fibromyalgia.
 Key words: calcium, magnesium, phosphorous, Fibromyalgia.

Magnesium and Fibromyalgia: A Literature Review

“…41,42 The challenges in assessing the magnesium status of the tissues have led to inconsistent relationships between magnesium levels and fibromyalgia with some studies showing no difference in magnesium levels between fibromyalgia patients and controls, others showing decreased levels and a few showing increased levels. 24-33…”

“…41,42 The challenges in assessing the magnesium status of the tissues have led to inconsistent relationships between magnesium levels and fibromyalgia with some studies showing no difference in magnesium levels between fibromyalgia patients and controls, others showing decreased levels and a few showing increased levels. [24][25][26][27][28][29][30][31][32][33] In most of the trials that explored the effect of magnesium on fibromyalgia, magnesium was given along with other interventions. 14,36,37,39,40 Only a few studies used magnesium as a single intervention.…”

“…Some studies showed decreased magnesium levels in several tissue compartments in fibromyalgia patients along with a negative correlation between magnesium levels and the clinical parameters of fibromyalgia. [24][25][26][27] Bagis el al 24 reported significantly lower serum and erythrocyte magnesium levels in patients with fibromyalgia compared to controls, along with a negative correlation between the magnesium levels and fibromyalgia symptoms. In Kasim's 25 study, serum magnesium levels were significantly lower in patients with fibromyalgia when compared to normal healthy individuals.…”

“…[24][25][26][27] Bagis el al 24 reported significantly lower serum and erythrocyte magnesium levels in patients with fibromyalgia compared to controls, along with a negative correlation between the magnesium levels and fibromyalgia symptoms. In Kasim's 25 study, serum magnesium levels were significantly lower in patients with fibromyalgia when compared to normal healthy individuals. Kim et al 26 found that concentrations of magnesium in the hair of female patients with fibromyalgia are significantly lower than of controls, even after adjustment of potential confounding factors.…”