Calcium Supplementation During Pregnancy for Preventing Hypertensive Disorders Is not Associated with Changes in Platelet Count, Urate, and Urinary Protein: a Randomized Control Trial

Hofmeyr, G Justus; Mlokoti, Z; Nikodem, V.C.; Mangesi, Lindeka; Ferreira, Sandra Roberta Gouvêa; Singata, Mandisa; Jafta, Zukiswa; Merialdi, Mario; Hazelden, C; Villar, José

doi:10.1080/10641950701826802

Cited by 31 publications

(17 citation statements)

References 4 publications

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“…Recent evidence indicates that calcium supplementation affects uteroplacental blood flow by lowering the resistance index in uterine and umbilical arteries . Calcium supplementation in the second half of pregnancy appears to reduce blood pressure directly rather than preventing the endothelial damage associated with pre‐eclampsia …”

Section: Prevention Of Pre‐eclampsiamentioning

confidence: 99%

SOMANZ guidelines for the management of hypertensive disorders of pregnancy 2014

Löwe

Bowyer

Lust

et al. 2015

Aust NZ J Obst Gynaeco

298

330

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This guideline is an evidence based, practical clinical approach to the management of Hypertensive Disorders of Pregnancy. Since the previous SOMANZ guideline published in 2008, there has been significant international progress towards harmonisation of definitions in relation to both the diagnosis and management of preeclampsia and gestational hypertension. This reflects increasing knowledge of the pathophysiology of these conditions, as well as their clinical manifestations. In addition, the guideline includes the management of chronic hypertension in pregnancy, an approach to screening, advice regarding prevention of hypertensive disorders of pregnancy, and discussion of recurrence risks and long term risk to maternal health. The literature reviewed included the previous SOMANZ Hypertensive Disorders of Pregnancy guideline from 2008 and its reference list, plus all other published National and International Guidelines on this subject. Medline, Cochrane Database of Systematic Reviews (CDSR), Cochrane Central Registry of Controlled Trials (CCRCT), National Institute for Health and Care Excellence (NICE) Evidence Search, and Database of Abstracts and Reviews of Effects (DARE) were searched for literature published between January 2007 and March, 2014.

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Section: Prevention Of Pre‐eclampsiamentioning

confidence: 99%

SOMANZ guidelines for the management of hypertensive disorders of pregnancy 2014

Löwe

Bowyer

Lust

et al. 2015

Aust NZ J Obst Gynaeco

298

330

View full text Add to dashboard Cite

show abstract

“…Calcium supplementation in the second half of pregnancy seems to reduce blood pressure directly, but does not prevent the endothelial damage associated with preeclampsia [71]. …”

Section: Calciummentioning

confidence: 99%

Prevention of Preeclampsia

Moura

Lopes

Murthi

et al. 2012

Journal of Pregnancy

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“…Evidence substantiating the finding is also present [19]. So oral calcium supplement of at least 1g/day is recommended 20 .…”

Section: Calciummentioning

confidence: 78%

Antihypertensive in Pregnancy-Pharmacotherapy Options

Anand¹

2014

Biomed. Pharmacol. J.

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Calcium Supplementation During Pregnancy for Preventing Hypertensive Disorders Is not Associated with Changes in Platelet Count, Urate, and Urinary Protein: a Randomized Control Trial

Abstract: An effect of calcium supplementation in the second half of pregnancy on the rate of abnormal laboratory measures associated with preeclampsia was not demonstrated.

Cited by 31 publications

References 4 publications

SOMANZ guidelines for the management of hypertensive disorders of pregnancy 2014

SOMANZ guidelines for the management of hypertensive disorders of pregnancy 2014

Prevention of Preeclampsia

Antihypertensive in Pregnancy-Pharmacotherapy Options

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