Calculated CT Volumes of Lacrimal Glands in Normal Korean Orbits

Min, Seong Gyu; Ha, Myung Sook

doi:10.3341/jkos.2015.56.1.1

Cited by 4 publications

(3 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…According to previous studies of An et al [ 10 ], the lacrimal gland size decreases with age. The lacrimal gland size of healthy Korean individuals has been reported using brain computed tomography (CT) angiography [ 10 ] and three-dimensional orbital CT scans [ 11 ].…”

mentioning

confidence: 99%

The Change of Lacrimal Gland Volume in Korean Patients with Thyroid-associated Ophthalmopathy

Huh

Kim

et al. 2016

Korean J Ophthalmol

View full text Add to dashboard Cite

PurposeTo describe the change of lacrimal gland volumes in Korean patients with thyroid-associated ophthalmopathy (TAO) via computed tomography (CT).MethodsA retrospective review of CT images from 217 TAO patients and 135 control subjects was performed. The TAO patients were diagnosed between May 2005 and May 2014 and had a CT performed on initial presentation (330 orbital CT scans). These images were compared with 270 orbital CT scans from the control group, obtained between May 2013 and May 2014. An open source DICOM viewer was used to calculate the volume of the lacrimal gland.ResultsThe mean volume of the lacrimal gland in TAO patients was 0.816 cm3 in the right orbit (standard deviation [SD], 0.048) and 0.811 cm3 in the left orbit (SD, 0.051), with no significant difference between right and left (p = 0.192). However, significant differences were observed between TAO patients and healthy individuals (p < 0.001). There was no significant difference between mean lacrimal gland volumes of males (0.812 cm3; SD, 0.037) and females (0.816 cm3; SD, 0.029) (p = 0.513). There was a negative correlation between gland volume and age in TAO patients (Pearson r = -0.479, p = 0.00). The subjective tearing (right: r = 0.244, p = 0.018; left: r = 0.226, p = 0.024), corneal superficial punctate keratopathy (right: r = 0.192, p = 0.040; left: r = 0.206, p = 0.036), and exophthalmometry (right: r = 0.182, p = 0.032; left: r = 0.180, p = 0.046) correlated with lacrimal gland volume.ConclusionsThis study is the first to use CT images to calculate the lacrimal gland volume of Korean TAO patients. In TAO patients, the lacrimal gland volume was notably increased compared to control subjects. The lacrimal gland volume decreased with age, but there was no difference between gender and no difference between left and right. The lacrimal gland volume correlated with subjective tearing, corneal superficial punctate keratopathy and exophthalmometry.

show abstract

mentioning

confidence: 99%

The Change of Lacrimal Gland Volume in Korean Patients with Thyroid-associated Ophthalmopathy

Huh

Kim

et al. 2016

Korean J Ophthalmol

View full text Add to dashboard Cite

show abstract

“…Lacrimal gland atrophy, seen with CT scan, is age related in both men and women. 29,33,34 Mucin layer helps in maintaining moisture in the eye, aqueous layer maintains tear volume as it contains water, electrolytes and protein and lipid layer aids in stabilization of the tear film as it prevents tear evaporation. Dry eye affects women two to four times more than men and post-menopausal women are more prone to it.…”

Section: Dews Classifies Dry Eye Into Two Major Categoriesmentioning

confidence: 99%

Sex hormones and dry eye disease: Current update

Maurya

Gupta²,

Verma³

et al. 2021

IJOOO

View full text Add to dashboard Cite

Dry eye disease (DED) is a multifactorial disorder of the ocular surface that results in ocular discomfort, visual disturbance and damage to the ocular surface. It is one of the most common complaints in daily ophthalmic practice. The greater prevalence of dry eye in women compared to men suggests that sex hormones may have a role in this condition. Sex hormones; estrogen and androgens influence production of all components of the tear film including aqueous layer, lipid layer, and mucin layer. Various mechanisms such as decrease in hormonal levels, shift in feedback mechanisms, and changes in receptor receptivity interplay to alter the ocular surface homeostasis and subsequently result in DED. The purpose of this review is to briefly outline current scientific evidence on the influence of androgen and estrogen on the lacrimal and meibomian glands as well as on the ocular surface epithelia including conjunctival goblet cells during reproductive and menopausal periods. This article also outlines the updates regarding role of gonadal hormones in the treatment of dry eye.

show abstract

“…Magnetic resonance imaging (MRI) provides better soft tissue resolution, whereas computed tomography (CT) allows for better visualization of calcifications and bony changes. [ 1 5 ] Normative measurements of the globes and lacrimal glands of various ethnicities around the world have been documented. [ 6 7 8 9 10 11 12 ]…”

Section: Introductionmentioning

confidence: 99%

Relationship Between the Computed Tomographic Volumetry of the Eyeballs and Lacrimal Glands in a Nigerian Population

Idowu¹,

Onigbinde

Chen

et al. 2022

Journal of West African College of Surgeons

View full text Add to dashboard Cite

Aim: The aim of this article was to obtain measurements of the eyeballs/globes and lacrimal glands in normal subjects using cranial computed tomography (CT) scan. Understanding the normative approximations of these measurements could help in diagnosing and evaluating orbito-ocular pathologies. Materials and Methods: This retrospective study examined 220 globes/eyeballs and 220 lacrimal glands of 110 consecutive participants. The eyeball volume was calculated using both the ellipsoid and spherical formulas, whereas lacrimal gland volume was approximated using the ellipsoid formula only. Results: The mean age of the subjects was 51.18 ± 14.85 years and ranged from 22 to 85 years. The study population was 53.6% male ( n = 59) and 46.3% female ( n = 51). The mean volumes of all globes in this study were 5.82 ± 0.77 and 5.98 ± 0.75 cm3 using the ellipsoid and spherical formulae, respectively. The mean volume of all lacrimal glands was 0.42 ± 0.14 cm3 using the ellipsoid formula. The mean globe volumes using the ellipsoid and spherical formulae (6.02 ± 0.84 and 6.02 ± 0.84 cm3) in males were significantly larger than the corresponding mean globe volumes in females (5.59 ± 0.62 and 5.80 ± 0.65 cm3) ( P < 0.0001 and P = 0.001, respectively). There was no significant difference between the lacrimal gland volumes of males (0.42 ± 0.14 cm3) and females (0.42 ± 0.14 cm3) ( P = 0.84). Conclusion: Males have larger eyeball/globe volumes than females. Eyeball and lacrimal gland volumes did not correlate significantly. Eyeball volume showed an inverse relationship with age. Age did not affect lacrimal gland volume.

show abstract

Calculated CT Volumes of Lacrimal Glands in Normal Korean Orbits

Cited by 4 publications

References 12 publications

The Change of Lacrimal Gland Volume in Korean Patients with Thyroid-associated Ophthalmopathy

The Change of Lacrimal Gland Volume in Korean Patients with Thyroid-associated Ophthalmopathy

Sex hormones and dry eye disease: Current update

Relationship Between the Computed Tomographic Volumetry of the Eyeballs and Lacrimal Glands in a Nigerian Population

Contact Info

Product

Resources

About