Calculated Dietary Intakes of Nitrate And Nitrite By Young Finns

Laitinen, Sirpa H.; Virtanen, Suvi Μ.; Rásänen, Leena; Penttilä, P.‐L.

doi:10.1080/02652039309374170

Cited by 19 publications

(4 citation statements)

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“…Nitrate (NO 3 − ) is white crystalline powder and also naturally occurring compounds present in various form in the environment. It has been also proved that nitrates present in fruits and vegetables [30] , [42] . WHO recommended that the daily intake (ADI) for nitrate should be 3.67 mg/kg body weight and for nitrite it must not be greater than 0.13 mg/kg body weight (WHO, 1973) because higher concentration of nitrates has caused cancer in adults and increased the possibility of brain tumour, leukaemia, and nasopharyngeal [50] , [8] .…”

Section: Introductionmentioning

confidence: 96%

Assessment of genotoxicity of some common food preservatives using Allium cepa L. as a test plant

2014

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Food preservatives play important role in today's food supplies that are used to prolong the self-life of products by protecting them from deterioration caused by micro-organisms. In this study, investigations were carried out to study the impacts of food preservatives like butylated hydroxytoluene, butylated hydroxyanisole, sorbic acid, propyl gallate and sodium nitrate. The effects of these preservatives at concentration of 1000 ppm, 1500 ppm, 2000 ppm, 2500 ppm for 4 h, 8 h and 16 h of exposure period were studied on the root tips of Allium cepa. Cytological studies revealed statistically significant (p < 0.05) inhibition in mitotic index with an increase in concentration of the food preservatives when compared with the control. Most frequent cytological abnormalities observed were bridges, multipolarity, C-mitosis, stickiness and cell death. The total percentages of abnormalities were also increased with increasing concentration and time duration. The abnormalities (%) in root system caused by used preservatives were recorded as butylated hydroxytoluene < butylated hydroxyanisole < sodium nitrate < sorbic acid < propyl gallate.

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Section: Introductionmentioning

confidence: 96%

Assessment of genotoxicity of some common food preservatives using Allium cepa L. as a test plant

2014

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“… Sang et al (2019) found that the contribution rates of drinking water and food sources accounted for 0.08 and 0.69% of endogenous NDMA in Chinese subjects. Endogenous NDMA also arises from the formation of NDMA in vivo from the consumption of meat and bacon cured with nitrite, nitrate-rich vegetables and seafood ( Laitinen et al, 1993 ; Dich et al, 1996 ; Zeilmaker et al, 2010 ). Post-mortem study of human subjects showed that endogenous NDMA is found in all tissues, including the brain ( Cooper et al, 1987 ).…”

Section: Discussionmentioning

confidence: 99%

Association of N-nitrosodimethylamine exposure with cognitive impairment based on the clues of mice and humans

Liu,

Huang,

Yan

et al. 2023

Front. Aging Neurosci.

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N-nitrosodimethylamine (NDMA) is an environmental and food contaminant, but limited data to concern whether NDMA has adverse effects on the brain. This study first determined the concentration of NDMA in foods from aquaculture markets in Shenzhen, then analyzed the effects on C57BL/6 mice and further evaluated on the urine samples of elderly Chinese residents with normal cognition (NC, n = 144), cognitive decline (CD, n = 116) and mild cognitive impairment (MCI, n = 123). The excessive rate of NDMA in foods was 3.32% (27/813), with a exceeding range of 4.78–131.00 μg/kg. Behavioral tests showed that 60 days treatment of mice with 3 mg/kg NDMA reduced cognitive performance. Cognitive impairment in human was significantly associated with sex, educational levels, length of residence in Shenzhen, household registration, passive smoking, rice, fresh vegetables, bacon products. NDMA was detected in 55.4% (212/383) of urine samples, with a median concentration of 0.23 μg/L (1.20 × 10 –7–157.39 μg/L). The median concentration for NC, CD and MCI were 0.32, 0.27, and 0 μg/L, respectively. The urinary NDMA concentration had a strong negative correlation with cognitive impairment (Kendall’s Tau-b = −0.89, P = 0.024). The median estimated daily intake (EDI) of NDMA was determined to be 6.63 ng/kg-bw/day. Taken together, there appears to be an association between NDMA and human and murine cognition, which provides a new clue to Alzheimer’s disease (AD).

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“…Este valor varia de acordo com os hábitos alimentares característicos de cada região. LAITINEN et al (1993) revelaram que 86% da ingestão de nitrato (NO 3 -) pelos finlandeses advêm dos vegetais, com um consumo diário de 54 mg de NO 3 -por pessoa.…”

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Composição centesimal e teor de nitrato em cinco cultivares de alface produzidas sob cultivo hidropônico

et al. 2009

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) RESUMOCom o objetivo de avaliar a qualidade nutricional de cinco cultivares de alface (Mimosa Verde, Mimosa Vermelha, Vera, Regina e Lucy Brown) produzidas em cultivo hidropônico sob sistema NFT, determinou-se sua composição centesimal e seu teor de nitrato. O delineamento experimental utilizado foi o inteiramente casualizado com quatro repetições. O experimento foi desenvolvido no Departamento de Engenharia Rural da Universidade Federal de Santa Catarina, Florianópolis (SC), de maio a julho de 2004. As bancadas de produção possuíam sete canais com 6,0 m de comprimento e 1,50 m de largura. O espaçamento utilizado foi 0,25 m e canais e 0,25 m entre plantas no canal. A colheita foi efetuada aos 54 dias após a semeadura, e permanência por 24 dias na bancada de produção. Na cultivar de alface do tipo americana, Lucy Brown, observou-se maior teor de água da parte aérea e também maior teor de nitrato. Nas cultivares Mimosa Vermelha e Mimosa Verde verificaram, em média, maior teor de fitomassa seca da parte aérea, de lipídios, de proteína e maior valor calórico. Na cultivar Mimosa Vermelha constatou-se maior teor de carboidratos e na Mimosa Verde, o maior teor de resíduo mineral, não diferindo da cultivar Regina. O maior teor de fibra foi constatado na cultivar Regina.Palavras-chave: hidroponia, Lactuca sativa L., nitrato e composição centesimal. ABSTRACT CENTESIMAL COMPOSITION AND NITRATE CONTENT IN FIVE CULTIVARS OF LETTUCE PRODUCED IN HYDROPONIC SYSTEMThe nutrition quality of five different lettuce cultivars (Mimosa Verde, Mimosa Vermelha, Vera, Regina and Lucy Brown) produced under NFT (Laminar Flow of Solution) system was determined by their centesimal composition and nitrate content. To analyze the experimental treatments it was used a completely randomized design with four replications. The experiment was developed in a greenhouse belonging to the Department of Agricultural Engineering of the Federal University of Santa Catarina, Florianópolis, Santa Catarina State, Brazil, from May to July of 2004 (autumn-winter period). The lettuces were grown in a group of benches (3% declivity) with seven canals (6.0 m length and 1.50 m width) where the nutritional solution would circulate. The space used was 0.25 m between canals and 0.25 m between plants in the canal, thus in each canal 24 plants had been lodged, totalizing 168 per bench. The circulation of the nutritional solution was controlled by a timer, which set in motion the joint motion-bomb in intervals preset in a turn 24-hour. The harvest was effected 54 days after the sowing, having remained per 24 days in the production group of benches. The American type of lettuce 'Lucy Brown', also presented a greater water content in its shoot as well as nitrate content than the others. Mimosa Vermelha and Mimosa Verde cultivars had on average, greater dry mass content theirs of shoots, as well as lipids, protein and caloric value than the others. 'Mimosa Vermelha' presented greater carbohydrates content and 'Mimosa Verde' the greater mineral residue content, but not dif...

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Calculated Dietary Intakes of Nitrate And Nitrite By Young Finns

Cited by 19 publications

References 15 publications

Assessment of genotoxicity of some common food preservatives using Allium cepa L. as a test plant

Assessment of genotoxicity of some common food preservatives using Allium cepa L. as a test plant

Association of N-nitrosodimethylamine exposure with cognitive impairment based on the clues of mice and humans

Composição centesimal e teor de nitrato em cinco cultivares de alface produzidas sob cultivo hidropônico

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