The relevance of the study is conditioned by the connection of the topic of slavery in the modern world with social rules, because it helps to understand the challenges and problems associated with racism, inequality, and social justice. In this regard, the purpose of the study was to explore the development of economic, cultural, and social life in the Atlantic region during the spread and after the abolition of slavery. The leading methods of investigating this problem are cultural and historical analysis, comparison, classification, synthesis, historical approach, deduction, and generalisation of results. The paper shows the content and functions of slavery; analyses the historical trends in the development of the slave trade, identifies its main factors; demonstrates the findings of modern historians and economists who considered aspects of changing views on slavery in different periods, dominant motives, features, nature and dynamics of the development of discriminatory attitudes in the Atlantic region; describes how slavery took root in America at the earliest stages of the European conquest; traces its characteristics, the origin of various systems, working conditions and exploitation; reveals changes in views on slavery as a negative way of building society; shows the interweaving of Atlantic slavery, the production of knowledge and colonisation, which influenced the development of the modern world; revealed a fair future through alternative anthropology solving complex issues and paying reparations; analysed in detail the development and changes in the economy, trade, social relations, and culture during the development of the slave trade; diagnosed that the cessation and eradication of slavery significantly affected the progress in the economic and cultural life of the United States and completed the period of expansion. The materials of the study are of scientific value for historians, economists, culturologists, and linguists who will be able to deepen research on the economic and cultural consequences of slavery, its impact on economic development, trade, literature, and art