Calculation of Dose, Dose Equivalent, and Relative Biological Effectiveness for High Charge and Energy Ion Beams

Wilson, John W.; Reginatto, Marcel; Hajnal, F.; Chun, Sang Y.

doi:10.1097/00004032-199504000-00010

Cited by 8 publications

(7 citation statements)

References 17 publications

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“…These simple approaches exhibit certain deficiencies. For example, the model by Wilson et al (1995a) does not reproduce accurately the experimental dose distributions (the differences are of the order of 20% for a 20 Ne beam of 670 MeV u −1 ), whereas the model of Sihver et al shows good agreement with measured depth dose data and dose average LET distributions in water, but it fails to correctly reproduce the production of light secondaries such as n, p, d, t and α particles.…”

Section: Deterministic Methods For Ion Transport In Mattermentioning

confidence: 98%

“…Heavy ion transport in complex media has also been treated using a deterministic approach developed at the NASA Langley Research Center. This line of research, which started about 20 years ago, has yielded a family of radiation transport codes mainly dedicated to solving engineering problems in radiation-shielding analysis for space missions (Wilson et al 1984(Wilson et al , 1995a(Wilson et al , 2002. One of these deterministic codes is the high-charge-and-energy transport code HZETRN, based on the one-dimensional formulation of the Boltzmann transport equation with a straight-ahead approximation (Wilson et al 1995b).…”

Section: Deterministic Methods For Ion Transport In Mattermentioning

confidence: 99%

“…In some research centres, deterministic methods for ion transport in tissue-like media have been developed as a part of the physics program of heavy ion therapy projects (Sihver et al 1998, Krämer et al 2000 or for prediction of radiation doses to astronauts on long-term space missions (Wilson et al 1984(Wilson et al , 1995a. In general, these methods, which are based on onedimensional transport theory, evaluate nuclear fragmentation processes using semi-empirical reaction cross sections.…”

Section: Deterministic Methods For Ion Transport In Mattermentioning

confidence: 99%

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Ion beam transport in tissue-like media using the Monte Carlo code SHIELD-HIT

et al. 2004

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The development of the Monte Carlo code SHIELD-HIT (heavy ion transport) for the simulation of the transport of protons and heavier ions in tissue-like media is described. The code SHIELD-HIT, a spin-off of SHIELD (available as RSICC CCC-667), extends the transport of hadron cascades from standard targets to that of ions in arbitrary tissue-like materials, taking into account ionization energy-loss straggling and multiple Coulomb scattering effects. The consistency of the results obtained with SHIELD-HIT has been verified against experimental data and other existing Monte Carlo codes (PTRAN, PETRA), as well as with deterministic models for ion transport, comparing depth distributions of energy deposition by protons, 12C and 20Ne ions impinging on water. The SHIELD-HIT code yields distributions consistent with a proper treatment of nuclear inelastic collisions. Energy depositions up to and well beyond the Bragg peak due to nuclear fragmentations are well predicted. Satisfactory agreement is also found with experimental determinations of the number of fragments of a given type, as a function of depth in water, produced by 12C and 14N ions of 670 MeV u(-1), although less favourable agreement is observed for heavier projectiles such as 16O ions of the same energy. The calculated neutron spectra differential in energy and angle produced in a mimic of a Martian rock by irradiation with 12C ions of 290 MeV u(-1) also shows good agreement with experimental data. It is concluded that a careful analysis of stopping power data for different tissues is necessary for radiation therapy applications, since an incorrect estimation of the position of the Bragg peak might lead to a significant deviation from the prescribed dose in small target volumes. The results presented in this study indicate the usefulness of the SHIELD-HIT code for Monte Carlo simulations in the field of light ion radiation therapy.

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Section: Deterministic Methods For Ion Transport In Mattermentioning

confidence: 98%

Section: Deterministic Methods For Ion Transport In Mattermentioning

confidence: 99%

Section: Deterministic Methods For Ion Transport In Mattermentioning

confidence: 99%

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Ion beam transport in tissue-like media using the Monte Carlo code SHIELD-HIT

et al. 2004

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“…Ronningen (4) , and K. Ieki (5) I. INTRODUCTION Advancements in heavy-ion accelerators over the last 30 years have led to the development of several new areas of research, such as hadron radiotherapy for cancer patients, shielding design studies for deep space missions, and the design and construction of high-intensity radioactive beam facilities.…”

Section: Heilbronnmentioning

confidence: 99%

“…It has yielded a family of radiation transport codes mainly dedicated to solving engineering problems in radiationshielding analysis for space missions. [4][5][6] One of these deterministic codes is the highcharge-and-energy transport code HZETRN, based on the one-dimensional formulation of the Boltzmann transport equation with a straight-ahead approximation 7 and a semiempirical abrasion-ablation fragmentation model for nuclear fragmentation processes.…”

Section: Heilbronnmentioning

confidence: 99%

Secondary Neutron-Production Cross Sections from Heavy-Ion Interactions between 230 and 600 MeV/Nucleon

Heilbronn

Zeitlin

Iwata³

et al. 2007

Nuclear Science and Engineering

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-Secondary neutron-production cross-sections have been measured from interactions of 230 MeV/nucleon He, 400 MeV/nucleon N, 400 MeV/nucleon Kr, 400MeV/nucleon Xe, 500 MeV/nucleon Fe, and 600 MeV/nucleon Ne interacting in a variety of elemental and composite targets. We report the double-differential production cross sections, angular distributions, energy spectra, and total cross sections from all systems. Neutron energies were measured using the time-of-flight technique, and were measured at laboratory angles between 5° and 80°. The spectra exhibit behavior previously reported in other heavy-ion-induced neutron production experiments; namely, a peak at forward angles near the energy corresponding to the beam velocity, with the remaining spectra generated by preequilibrium and equilibrium processes. The doubledifferential spectra are fitted with a moving-source parameterization. Observations on the dependence of the total cross sections on target and projectile mass are discussed.

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