Calendula Officinalis-An Important Medicinal Plant with Potential Biological Properties

Jan, Nelofer; John, Riffat

doi:10.16943/ptinsa/2017/49126

Cited by 48 publications

(34 citation statements)

References 18 publications

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“…The flowers of Calendula officinalis , known as pot marigold, are used in traditional folk medicine in the preparation of aqueous extract, ointments, among others, especially for treating inflammations and wounds [11]. Jan et al [12] reported that C. officinalis is an important medicinal plant with diverse phytochemicals and biological activities, such as antioxidant, anti-inflammatory, antibacterial, gastroprotective, and hepatoprotective. Among the phytochemicals present in flowers of C. officinalis , the triterpenes [13], flavonoids [13,14,15], phenolic acids [13,15], quinones and coumarins [16], and carotenoids [16,17] stand out.…”

Section: Introductionmentioning

confidence: 99%

From the Field to the Pot: Phytochemical and Functional Analyses of Calendula officinalis L. Flower for Incorporation in an Organic Yogurt

et al. 2019

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Edible flowers have been used as ingredients because of their biological activities, taste, and overall appearance. This research was aimed to characterize the chemical composition and in vitro antioxidant activity of the marigold flower (Calendula officinalis L.) extracted with different proportions of water and ethyl alcohol, and the lyophilized extract with higher content of antioxidant compounds was incorporated into an organic yogurt. Results showed that the hydroalcoholic extract (50:50 v/v) presented the highest total phenolic content (TPC), flavonoids, and antioxidant activity (ferric reducing antioxidant power (FRAP), total reducing capacity (TRC), and Cu2+/Fe2+ chelating ability). Phenolic acids and flavonoids were quantified in the extract by LC-DAD, while 19 compounds were tentatively identified by ESI-MS/MS. The lyophilized marigold extract (LME) also inhibited 12% of Wistar rat’s brain lipid oxidation in vitro, inhibited α-amylase, and α-glucosidase activities, but showed no cytotoxicity towards cancerous cells (HCT8 and A549). However, marigold flower extract protected human erythrocytes against mechanical stress. When added into an organic yogurt model (0 to 1.5%), LME increased TPC and antioxidant activity (2,2-diphenyl-1-picrylhydrazyl (DPPH) and TRC), and the sensory analysis showed that the organic yogurt had an acceptance of 80.4%. Our results show that the use of LME may be a technological strategy to increase the content of bioactive compounds in yogurts.

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Section: Introductionmentioning

confidence: 99%

From the Field to the Pot: Phytochemical and Functional Analyses of Calendula officinalis L. Flower for Incorporation in an Organic Yogurt

et al. 2019

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“…[ 34 , 35 , 36 , 37 , 38 , 39 ]. Calendula officinalis flower extract, owing to its complex composition ( Figure 1 ), possess multiple activities, including antioxidant, antibacterial, antifungal, antiviral, anti-inflammatory, antioedematous, and wound healing activities, as well as immunostimulant, anticancer, hepatoprotective, and insecticidal properties [ 40 , 41 , 42 , 43 , 44 , 45 ]. For these reasons, pot marigold is used in the treatment of numerous skin injures, such as burns, ulcers, skin inflammations, eczema, bruises, cuts, and abrasions of the epidermis, rashes, skin wounds, frostbites, and other conditions [ 46 , 47 , 48 , 49 , 50 , 51 ].…”

Section: Introductionmentioning

confidence: 99%

Design of Sodium Alginate/Gelatin-Based Emulsion Film Fused with Polylactide Microparticles Charged with Plant Extract

Prus-Walendziak

Kozłowska

2021

Materials

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This study aimed at designing emulsion films based on sodium alginate, gelatin, and glycerol, and their modification by the addition of lipids (cottonseed oil and beeswax). Film composition with the most promising properties was further modified by the incorporation of polylactide (PLA) microparticles with Calendula officinalis flower extract. PLA microspheres were obtained by the emulsion/solvent evaporation method. The size distribution of oily particles in emulsions was investigated. Mechanical properties, moisture content, UV-Vis spectra, and the color of films were analyzed, while biophysical skin parameters were assessed after their application to the skin. Moreover, the contact angles were measured, and the surface free energy of polymeric films was determined. An investigation of the amount of Calendula officinalis flower extract which can be incorporated into PLA microparticles was performed. The modification of the composition of films significantly influenced their physicochemical properties. The selected active ingredient in the form of plant extract was successfully incorporated into polymeric microparticles that were further added into the developed emulsion film. The condition of the skin after the application of obtained emulsion films improved. The prepared materials, especially containing microparticles with plant extract, can be considered for designing new cosmetic forms, such as cosmetic masks, as well as new topical formulations for pharmaceutical delivery.

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“…Several classes of biochemical compounds were identified in C. officinalis inflorescences including essential oil, carotenoids, flavonoids, terpenoids, coumarins, quinones, amino acids, lipids, and carbohydrates. These compounds can be used for various pharmaceutical and medicinal purposes: as an anti-oxidant, anti-inflammatory, anti-bacterial, anti-fungal, anti-cancer, anti-HIV, to promote wound healing, and more (Khalid and da Silva, 2012;Jan and John, 2017;Cruceriu et al, 2018;Verma et al, 2018;Givol et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

Artificial Chromosome Doubling in Allotetraploid Calendula officinalis

et al. 2020

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Calendula officinalis L. is known as an ornamental plant as well as a source of biochemical compounds used in cosmetics and industry. C. officinalis has a complex karyotype. Published chromosome numbers differ between 2n = 4x = 28 or 32. We have estimated genome sizes in nine commercial cultivars and evaluated the ploidy level by karyotyping and fluorescent in situ hybridization (FISH) using 5S and 45S rDNA loci. The detection of chromosome sets of two rather than four homologues would suggest that C. officinalis has an allotetraploid background. In addition, four signals for 45S but only two for 5S were found by using FISH. Artificial chromosome doubling is a common technique in plant breeding, as polyploidization results in several consequences for plant growth and development. Especially the suggested allotetraploid background in C. officinalis is interesting when examining the effect of chromosome doubling on the plant phenotype. Here we describe chromosome doubling of three allotetraploid cultivars of C. officinalis, 'Nova,' 'WUR 1553-7' and 'Orange Beauty'. Three antimitotic agents-colchicine, oryzalin and trifluralin-were used in different concentrations to find the combination of the best agent and the best dosage to obtain octaploids. For all three cultivars a few octaploids were obtained. A concentration of 200 and 400 ppm of colchicine was most efficient for chromosome doubling in 'Nova' and 'Orange Beauty,' respectively. For 'WUR 1553-7' the treatment with 20 ppm oryzalin was also effective. Cell numbers and first observations of the phenotype in the chromosome doubled plants show thicker leaves and bigger cells, as commonly observed after ploidy doubling. Due to the low number of chromosome doubled plants obtained more elaborate phenotyping will be performed on following generations cultivated under field conditions.

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Calendula Officinalis-An Important Medicinal Plant with Potential Biological Properties

Cited by 48 publications

References 18 publications

From the Field to the Pot: Phytochemical and Functional Analyses of Calendula officinalis L. Flower for Incorporation in an Organic Yogurt

From the Field to the Pot: Phytochemical and Functional Analyses of Calendula officinalis L. Flower for Incorporation in an Organic Yogurt

Design of Sodium Alginate/Gelatin-Based Emulsion Film Fused with Polylactide Microparticles Charged with Plant Extract

Artificial Chromosome Doubling in Allotetraploid Calendula officinalis

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