The Fusion and Astrophysics (FAST) Data and Diagnostic Calibration Facility located at the Lawrence Livermore National Laboratory is a state-of-the-art facility used to calibrate radiation based diagnostics and study atomic processes for investigating fusion and astrophysical plasmas. FAST has at its disposal a full suite of radiation generation and detection devices, including two electron beam ion traps: EBIT-I and SuperEBIT and an absolutely calibrated x-ray calorimeter spectrometer. FAST covers the energy range between 0.01 and 100 keV, and can thus be used to calibrate a variety of plasma diagnostics. Instrument parameters that can be calibrated include line profiles, transmission and reflection efficiencies, and the quantum efficiency of grating and crystal spectrometers and solid state detectors. FAST can be used to test fully integrated instrumentation, and is ideal for spectrometers and detectors to be flown on orbiting observatories, sounding rockets, used as ground support equipment to verify flight instrumentation, in laboratory astrophysics experiments, and to diagnose magnetic and inertial confinement fusion plasmas. Here we present an overview of the calibration capabilities of this facility including some results.