Calibration of ion-selective microelectrodes for use with high levels of interfering ions

Salt, Alec N.; Vora, Arti

doi:10.1016/0165-0270(91)90173-w

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Self-referencing Ion Selective (Seris) Probes1

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2006

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Cited by 16 publications

(1 citation statement)

References 9 publications

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“…Thus, in an extracellular medium as defined by Ammann et al (1987), a 1.1 mmol и l -1 Ca 2ϩ concentration will have an activity of only 0.37 mmol · l -1 Ca 2ϩ . In strict terms, therefore, the electrodes respond to activity but where the activity coefficient of the test solution is similar to the standard solutions conversion can be neglected (Salt and Vora, 1991).…”

Section: Self-referencing Ion Selective (Seris) Probesmentioning

confidence: 99%

Self-referencing, non-invasive, ion selective electrode for single cell detection of trans-plasma membrane calcium flux

Smith

Hammar

Porterfield

et al. 1999

Microsc. Res. Tech.

155

140

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Section: Self-referencing Ion Selective (Seris) Probesmentioning

confidence: 99%

Self-referencing, non-invasive, ion selective electrode for single cell detection of trans-plasma membrane calcium flux

Smith

Hammar

Porterfield

et al. 1999

Microsc. Res. Tech.

155

140

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Longitudinal fluid movements in the cochlea under normal and abnormal conditions

Salt¹

1996

Intracranial and Intralabyrinthine Fluids

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Tetramethylammonium for in vivo marking of the cross-sectional area of the scala media in the guinea pig cochlea

Salt

1992

Eur Arch Otorhinolaryngol

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A physiologic technique was developed to measure endolymphatic cross-sectional area in vivo using tetramethylammonium (TMA) as a volume marker. The technique was evaluated in guinea pigs as an animal model. In the method, the cochlea was exposed surgically and TMA was injected into endolymph of the second turn at a constant rate by iontophoresis. The concentration of TMA was monitored during and after the injection using ion-selective electrodes. Cross-section estimates derived from the TMA concentration measurements were compared in normal animals and animals in which endolymphatic hydrops had been induced by ablation of the endolymphatic duct and sac 8 weeks earlier. The method demonstrated a mean increase in cross-sectional area of 258% in the hydropic group. Individually measured area values were compared with action potential threshold shifts and the magnitude of the endocochlear potential (EP). Hydropic animals typically showed an increase in threshold to 2 kHz stimuli and a decrease in EP. However, the degree of threshold shift or EP decrease did not correlate well with the degree of hydrops present.

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Calibration of ion-selective microelectrodes for use with high levels of interfering ions

Cited by 16 publications

References 9 publications

Self-referencing, non-invasive, ion selective electrode for single cell detection of trans-plasma membrane calcium flux

Self-referencing, non-invasive, ion selective electrode for single cell detection of trans-plasma membrane calcium flux

Longitudinal fluid movements in the cochlea under normal and abnormal conditions

Tetramethylammonium for in vivo marking of the cross-sectional area of the scala media in the guinea pig cochlea

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