Calix[4]arene derivatives as stationary phases for capillary gas chromatography

Abstract

SummaryTwo new kinds of calix [4]arene derivatives, 5,11,17,23-tetra-tert-butyl-25,27-bis(isopropylcarbamoyl-meth- . These stationary phases demonstrate high column efficiencies, wide operating temperature ranges, good thermal stability and excellent selectivity for aromatic isomers, especially phenol compounds. Their inclusion properties are also discussed.

Separation of Aromatic Isomers by Capillary Gas Chromatography with Two Calix[4]arene Polysiloxane Stationary Phases

“…Derivatization being a practicable method to improve the solubility, a few reports are available using modified calixarene as stationary phase in gas chromatography. 16 In this paper, two new telomers, containing respectively cone bis(undecenyloxy)-p-t-butyl calix [4]crown-5 poly siloxanes (PSO-C-c [4]c-5) and partial cone 5,11,17,23-t-butyl-25,27-diethoxy-26,28-diundecenyl calix [4]arene polysiloxane (PSO-PC-c[4]E), are synthesized in a new way and used as stationary phase for capillary gas chromatography. The new stationary phases exhibit excellent column efficiency, thermal stability and unique selectivity in separating many aromatic compounds, especially for positional isomers.…”

Preparation and Characterization of a New p-tert-Butyl-calix[8]arene-bonded Stationary Phase for High-Performance Liquid Chromatography

“…1,2 In recent years, the potential of this class of macrocycles has also been shown for several applications in gas chromatography (GC), highperformance liquid chromatography (HPLC) and capillary electrophoresis. [3][4][5][6] The results show that the recognition of calixarenes for many solutes facilitates to improve the separation selectivity. 7 In 1993, Glennon and coworkers [8][9][10] prepared silica-bonded calix [4]arene tetraester and silica-bonded calix [4]arene tetradiethylamide stationary phases to separate metal ions and amino acid esters for the first time.…”

Applications of Nano-Baskets of Calixarenes in Chromatography

“…In their experiments, p-tert-butylcalix [8]arene exhibited selectivity toward chloromethanes. Lin et al [117] and Lai et al [118] synthesized 5,11,17,23-tetra-tert-butyl-25,27-bis(isopropylcarbamoylmethoxy)-26,28-diundecenyloxycalix [4]arene and 25, 27-dibutoxy-5,11,17,23-tetra-tert-butyl-26,28-diundecenyloxycalix [4]arene, and used them with capillary columns containing 14% cyanopropylphenyl methylpolysiloxane (OV-1701) as stationary phases in capillary gas chromatography. They showed wide operating temperature ranges, high column efficiencies, good thermal stability and excellent selectivity for aromatic isomers (especially phenol compounds).…”