Calixarene‐Based Nanoscale Coordination Cages

Abstract

Molecular shuttlecocks: The introduction of tripodal ternary acids (red; see picture) to the cobalt/calixarene (green) systems led to the formation of four unprecedented calixarene‐based nanoscale coordination cages through a [6+8] condensation. The overall periphery diameters of the nanocages ranged from 3.3 to 4.7 nm, and there were two sizes for the internal cavities (1.1 and 1.7 nm).

Investigating Subcellular Compartment Targeting Effect of Porous Coordination Cages for Enhancing Cancer Nanotherapy

“…23-27 The PCC structures usually exhibit a hydrophobic inner cavity, water stability, and size uniformity in solution. 28-32 As PCCs can carry guest molecules within these cavities and can release guest molecules as a result of their reversible bonds, PCCs are potential candidates for cellular cargo delivery vectors. These features are highly desired for photodynamic therapy and chemotherapy applications.…”

A Cobalt Supramolecular Triple-Stranded Helicate-based Discrete Molecular Cage

“…The rational design of single molecular structures using multi-nuclear metal clusters (these were described as “secondary building blocks” in the previous reports)181920212223 and various di- or multicarboxylate organic ligands has also been achieved242526272829303132333435. Despite the structural distinction, their preparative paradigms are commonly confined by the use of simple coordination modes involving the assemblies of metal ions and ligands (“primary” assembly)12131415161736 or multinuclear metal clusters and multifunctional ligands (“secondary” assembly)181920212223242526272829303132333435 (Fig. 1).…”

Influencing the Orientation of Jahn–Teller Axes in Butterfly‐Like MnIII4 Clusters

“…[1,2] We have explored this chemistry extensively with ptert-butyl-calix[4]arene/calix[4]arene (TBC[4]/C[4]) in particular and have reported a range of novel cluster motifs including: 1) [] This study has allowed us to establish a set of metal-ion binding rules for the general C[4] framework, and perhaps the most important feature of this is that the polyphenolic pocket shows strong affinity for Mn III ions in competition experiments. Specific properties of this ligand, in comparison to others in the literature, offer a route to influencing the orientation of the Jahn-Teller axes within this cluster motif, which possesses a rare oxidation state arrangement.…”

“…[1,2] We have explored this chemistry extensively with ptert-butyl-calix[4]arene/calix[4]arene (TBC[4]/C[4]) in particular and have reported a range of novel cluster motifs including: 1) [] This study has allowed us to establish a set of metal-ion binding rules for the general C[4] framework, and perhaps the most important feature of this is that the polyphenolic pocket shows strong affinity for Mn III ions in competition experiments. [1,2] We have explored this chemistry extensively with ptert-butyl-calix[4]arene/calix[4]arene (TBC[4]/C[4]) in particular and have reported a range of novel cluster motifs including: 1) [] This study has allowed us to establish a set of metal-ion binding rules for the general C[4] framework, and perhaps the most important feature of this is that the polyphenolic pocket shows strong affinity for Mn III ions in competition experiments.…”