Natural radioactivity is examined in soil samples collected from Northwestern Epirus, specifically in Pogoni and Zagori areas. The focus was to determine experimentally the specific activity for naturally occurring isotopes (40K, U and Th series) and the anthropogenic 137Cs, in the samples collected from a generally unexplored area of Greece. The measurements were carried out with the use of two High-Purity Germanium (HPGe) detectors, calibrated with two different bulk geometry samples. Based on the measurements of specific activities, the absorbed dosage and index of external hazard, Hex have been estimated through models of UNSCEAR, contributing to the level of environmental sustainability of the area.