Calmodulin binding transcription activators: An interplay between calcium signalling and plant stress tolerance

Noman, Muhammad; Jameel, Aysha; Ketehouli, Toi; Jiao, Yang; Du, Lina; Wang, Fawei; Li, Haiyan

doi:10.1016/j.jplph.2020.153327

Cited by 52 publications

(22 citation statements)

References 106 publications

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“…This change in the cytosolic Ca 2+ levels can be detected by numerous high-affinity calcium sensors. In higher plants, several families of Ca 2+ sensors have been recognised, including calmodulin (CaM) and CaM-related proteins [ 13 , 14 ], Ca 2+ dependent protein kinases (CDPKs) [ 15 , 16 ], and calcineurin B-like (CBL) proteins and their interacting protein kinases (CIPKs) [ 17 ]. CBL–CIPKs interactions transduce downstream signals to membrane effectors (various membrane ion channels, pumps, and transporters) which, in turn, facilitate ionic homeostasis by controlling ion uptake, long-distance transport, and sequestration [ 18 ].…”

Section: Introductionmentioning

confidence: 99%

Revealing the Role of the Calcineurin B-Like Protein-Interacting Protein Kinase 9 (CIPK9) in Rice Adaptive Responses to Salinity, Osmotic Stress, and K+ Deficiency

Shabala

Alnayef

Bose

et al. 2021

Plants

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In plants, calcineurin B-like (CBL) proteins and their interacting protein kinases (CIPK) form functional complexes that transduce downstream signals to membrane effectors assisting in their adaptation to adverse environmental conditions. This study addresses the issue of the physiological role of CIPK9 in adaptive responses to salinity, osmotic stress, and K+ deficiency in rice plants. Whole-plant physiological studies revealed that Oscipk9 rice mutant lacks a functional CIPK9 gene and displayed a mildly stronger phenotype, both under saline and osmotic stress conditions. The reported difference was attributed to the ability of Oscipk9 to maintain significantly higher stomatal conductance (thus, a greater carbon gain). Oscipk9 plants contained much less K+ in their tissues, implying the role of CIPK9 in K+ acquisition and homeostasis in rice. Oscipk9 roots also showed hypersensitivity to ROS under conditions of low K+ availability suggesting an important role of H2O2 signalling as a component of plant adaptive responses to a low-K environment. The likely mechanistic basis of above physiological responses is discussed.

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Section: Introductionmentioning

confidence: 99%

Revealing the Role of the Calcineurin B-Like Protein-Interacting Protein Kinase 9 (CIPK9) in Rice Adaptive Responses to Salinity, Osmotic Stress, and K+ Deficiency

Shabala

Alnayef

Bose

et al. 2021

Plants

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“…Plants have evolved various mechanisms to cope with stresses, and these include the shifts in the physiology of the plant and the expression of stress-associated genes, leading to the formation of a wide variety of low molecular mass metabolites collectively known as compatible solutes [ 2 ]. These solutes play a significant role in stress tolerance by preventing detrimental changes at cellular levels and the accumulation of these molecules actively or passively helps plants retain water and maintain turgor, protect protein structures, and stabilize cellular membranes under drought [ 2 , 40 , 41 , 42 , 43 , 44 , 45 ]. Among these osmolytes, proline is used in transgene-based research and is the main contributor to osmotic adjustments [ 46 ], although the molecular and cellular function of this solute is not entirely clear.…”

Section: Plant Stress-responsive Mechanisms During Drought and Other Abiotic Stressesmentioning

confidence: 99%

“…In an effort for plants to survive and fulfill the criteria for natural selection, the evolution originates at the DNA level, ramifying one gene into two, etc. to eventual speciation [ 43 , 44 ]. This leads to the continuous development of plant adaptation to environmental adversities at molecular, biochemical, physiological, and morphological levels.…”

Section: Plant Stress-responsive Mechanisms During Drought and Other Abiotic Stressesmentioning

confidence: 99%

“…After plants are exposed to stress, the stress signal is received on the cell surface receptor, whereby signal transduction occurs through the accumulation or release of Ca 2+ ions, and/or through the de novo synthesis of the second messenger molecules such as reactive oxygen species (ROS), inositol trisphosphates, hexaphosphate, and diacylglycerols [ 47 ]. These second messengers start regulating intracellular concentrations of cytosolic Ca 2+ ion levels that lead to the biosynthesis of Ca 2+ ion-binding proteins which activate calcium-dependent protein kinases (CDPKs) [ 48 ] and other relay proteins [ 44 ]. In turn, activated kinases and phosphatases initiate phosphorylation/de-phosphorylation of specific TFs, leading to the expression of stress-responsive genes [ 6 ].…”

Section: Plant Stress-responsive Mechanisms During Drought and Other Abiotic Stressesmentioning

confidence: 99%

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Plant Transcription Factors Involved in Drought and Associated Stresses

Hrmová

Hussain

2021

IJMS

122

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Transcription factors (TFs) play a significant role in signal transduction networks spanning the perception of a stress signal and the expression of corresponding stress-responsive genes. TFs are multi-functional proteins that may simultaneously control numerous pathways during stresses in plants—this makes them powerful tools for the manipulation of regulatory and stress-responsive pathways. In recent years, the structure-function relationships of numerous plant TFs involved in drought and associated stresses have been defined, which prompted devising practical strategies for engineering plants with enhanced stress tolerance. Vast data have emerged on purposely basic leucine zipper (bZIP), WRKY, homeodomain-leucine zipper (HD-Zip), myeloblastoma (MYB), drought-response elements binding proteins/C-repeat binding factor (DREB/CBF), shine (SHN), and wax production-like (WXPL) TFs that reflect the understanding of their 3D structure and how the structure relates to function. Consequently, this information is useful in the tailored design of variant TFs that enhances our understanding of their functional states, such as oligomerization, post-translational modification patterns, protein-protein interactions, and their abilities to recognize downstream target DNA sequences. Here, we report on the progress of TFs based on their interaction pathway participation in stress-responsive networks, and pinpoint strategies and applications for crops and the impact of these strategies for improving plant stress tolerance.

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“…Ca 2+ signaling networks are implicated in most abiotic stress responses in plants (Atif et al, 2019;Tang et al, 2020;Alves et al, 2021;Ma et al, 2021;Noman et al, 2021). However, there is mixed evidence to directly support a role for Ca 2+ signals as an initial heat sensing response (Gao et al, 2012;Tunc-Ozdemir et al, 2013;Finka and Goloubinoff, 2014;Lenzoni and Knight, 2019).…”

Section: Introductionmentioning

confidence: 99%

A Ratiometric Calcium Reporter CGf Reveals Calcium Dynamics Both in the Single Cell and Whole Plant Levels Under Heat Stress

et al. 2021

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Land plants evolved to quickly sense and adapt to temperature changes, such as hot days and cold nights. Given that calcium (Ca2+) signaling networks are implicated in most abiotic stress responses, heat-triggered changes in cytosolic Ca2+ were investigated in Arabidopsis leaves and pollen. Plants were engineered with a reporter called CGf, a ratiometric, genetically encoded Ca2+ reporter with an mCherry reference domain fused to an intensiometric Ca2+ reporter GCaMP6f. Relative changes in [Ca2+]cyt were estimated based on CGf’s apparent KD around 220 nM. The ratiometric output provided an opportunity to compare Ca2+ dynamics between different tissues, cell types, or subcellular locations. In leaves, CGf detected heat-triggered cytosolic Ca2+ signals, comprised of three different signatures showing similarly rapid rates of Ca2+ influx followed by differing rates of efflux (50% durations ranging from 5 to 19 min). These heat-triggered Ca2+ signals were approximately 1.5-fold greater in magnitude than blue light-triggered signals in the same leaves. In contrast, growing pollen tubes showed two different heat-triggered responses. Exposure to heat caused tip-focused steady growth [Ca2+]cyt oscillations to shift to a pattern characteristic of a growth arrest (22%), or an almost undetectable [Ca2+]cyt (78%). Together, these contrasting examples of heat-triggered Ca2+ responses in leaves and pollen highlight the diversity of Ca2+ signals in plants, inviting speculations about their differing kinetic features and biological functions.

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Calmodulin binding transcription activators: An interplay between calcium signalling and plant stress tolerance

Cited by 52 publications

References 106 publications

Revealing the Role of the Calcineurin B-Like Protein-Interacting Protein Kinase 9 (CIPK9) in Rice Adaptive Responses to Salinity, Osmotic Stress, and K+ Deficiency

Revealing the Role of the Calcineurin B-Like Protein-Interacting Protein Kinase 9 (CIPK9) in Rice Adaptive Responses to Salinity, Osmotic Stress, and K+ Deficiency

Plant Transcription Factors Involved in Drought and Associated Stresses

A Ratiometric Calcium Reporter CGf Reveals Calcium Dynamics Both in the Single Cell and Whole Plant Levels Under Heat Stress

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