2015
DOI: 10.1016/j.ijscr.2015.03.033
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Calvarial ectopic meningothelial meningioma

Abstract: HighlightsIntraosseous meningiomas may be confused with fibrous dysplasia and/or osteoid osteoma.Lesions appear either as osteoblastic or osteolytic lesions.Usually presents as a painless palpable mass associated with headaches.Embryological remnants of neuroectodermal tissue or cellular dedifferentiation seem to justify the lack of dural connections.Complete surgical excision is usually curative.

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Cited by 8 publications
(6 citation statements)
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“…The pathophysiology is not clarified, several theories have been proposed in the embryological development of the neural crest arachnoid precursors cells, their remnants are evidence of the failure in cranial migration, the mechanisms that originate ectopic meningiomas are: (1) failure in cell signaling to their destinations in arachnoid tissues, "staying in the middle of the road" (2) erroneous cell signaling implanting itself in tissues other than neural, (3) interruption of its migration paths by the presence of other abnormal cells that will form intracranial lesions, the latter two allow meningocytes to collide with mesenchymal and endodermal tissues and (4) the dedifferentiation of normal peripheral neural tissues to meningocytes, the latter less approved 9,10 ; the crash of neuroectodermal cells to the epithelium (endodermal origin) of the second pharyngeal bag which is the primordium of the palatine tonsils could occur between the third and fifth month of intrauterine period, a time when infiltration of lymphatic tissue in this structure also occurs 11 ; as a hypothesis applied in our case (Figure 2a).…”
Section: Cavity Tumors | Miscellaneous [[Q1: Q1]]mentioning
confidence: 99%
“…The pathophysiology is not clarified, several theories have been proposed in the embryological development of the neural crest arachnoid precursors cells, their remnants are evidence of the failure in cranial migration, the mechanisms that originate ectopic meningiomas are: (1) failure in cell signaling to their destinations in arachnoid tissues, "staying in the middle of the road" (2) erroneous cell signaling implanting itself in tissues other than neural, (3) interruption of its migration paths by the presence of other abnormal cells that will form intracranial lesions, the latter two allow meningocytes to collide with mesenchymal and endodermal tissues and (4) the dedifferentiation of normal peripheral neural tissues to meningocytes, the latter less approved 9,10 ; the crash of neuroectodermal cells to the epithelium (endodermal origin) of the second pharyngeal bag which is the primordium of the palatine tonsils could occur between the third and fifth month of intrauterine period, a time when infiltration of lymphatic tissue in this structure also occurs 11 ; as a hypothesis applied in our case (Figure 2a).…”
Section: Cavity Tumors | Miscellaneous [[Q1: Q1]]mentioning
confidence: 99%
“…[8,13] e diploe can be affected by various pathologies, such as bone cysts, encephaloceles, arachnoid cysts, lipomas, teratomas, dermoid, epidermoid, cavernous hemangiomas, metastatic tumors, neurofibromas, and meningiomas. [1][2][3][4][5][6][7][11][12][13][14][15][16][17][18][19][20][21][22][23][24]26] Intradiploic meningioma is an infrequent but distinct entity that commonly develops as a benign tumor. [1,2,[4][5][6][7]10,12,[16][17][18]20,21,26] Angiomatous meningioma is a rare subtype of the World Health Organization Grade I meningioma, characterized by tumor cells consistent with low-grade meningioma and prominent microvessels of varying sizes.…”
Section: Introductionmentioning
confidence: 99%
“…[1][2][3][4][5][6][7][11][12][13][14][15][16][17][18][19][20][21][22][23][24]26] Intradiploic meningioma is an infrequent but distinct entity that commonly develops as a benign tumor. [1,2,[4][5][6][7]10,12,[16][17][18]20,21,26] Angiomatous meningioma is a rare subtype of the World Health Organization Grade I meningioma, characterized by tumor cells consistent with low-grade meningioma and prominent microvessels of varying sizes. [9,25] To the best of our knowledge, there have been no reports documenting intradiploic angiomatous meningiomas.…”
Section: Introductionmentioning
confidence: 99%
“…The clinical management methods of calvarial lesions differ greatly depending on the underlying entity [ 17 ]. Most benign lesions, such as osteomas, meningiomas, or intraosseous hemangiomas, can usually be completely resected and do not need further treatment [ 5 , 16 , 18 , 23 ]. However, malignant lesions, such as metastasis or osteolysis in plasmacytoma, potentially require an adjuvant therapy such as chemotherapy, immunotherapy, or radiation [ 3 , 17 ].…”
Section: Introductionmentioning
confidence: 99%