Cambios en el síndrome coronario agudo en una década en un hospital de referencia provincial

Gómez-Barrado, José J.; Ortiz-Cortés, Carolina; Gómez-Turégano, Paula; Lezcano-Gort, Luis Enrique; Kounka, Zineb; Romero-Castro, María José

doi:10.1016/j.arteri.2019.07.001

Cited by 1 publication

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“…In Western countries, the incidence of myocardial infarction has decreased in recent years and long-term survival has improved [19,20]. However, patients with a previous myocardial infarction continue to have a high cardiovascular risk and it is estimated that one in five has a recurrent cardiovascular event in the following 10 years [21].…”

Section: Discussionmentioning

confidence: 99%

Low-Density Lipoprotein Cholesterol Targets in Patients With Coronary Heart Disease in Extremadura (Spain): LYNX Registry

et al. 2020

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Background: Low-density lipoprotein cholesterol (LDL-C) contributes decisively to the development of cardiovascular disease (CVD). In the LYNX registry we determined the rate of achievement of the target value of LDL-C, the use of lipid-lowering therapy (LLT) and the predictive factors of not reaching the target in patients with stable coronary heart disease (CHD). Methods: LYNX included consecutive patients with stable CHD treated at the University Hospital of Caceres, Extremadura (Spain) from September 2016 to September 2018, and those who must have an LDL-C target below 70 mg/dL according to the European Society of Cardiology (ESC) 2016 guidelines. The variables independently associated with the breach of the LDL-C objective were evaluated by multivariable logistic regression. Results: A total of 674 patients with stable CHD were included. The average LDL-C levels were 68.3 ± 24.5 mg/dL, with 56.7% showing a level below 70 mg/dL. LLT was used by 96.7% of patients, 71.7% were treated with high-powered statins and 30.1% with ezetimibe. The risk of not reaching the target value of LDL-C was higher in women, in active smokers, and in those who had multivessel CHD or had atrial fibrillation. Patients with diabetes mellitus, those who took potent statins or co-administration treatment with ezetimibe were more likely to reach the target level of LDL-C. Conclusions: The treatment of dyslipidemia in patients with chronic CHD remains suboptimal; however, an increasing number of very high-risk patients achieve the LDL-C objective, although there is still enormous potential to improve cardiovascular outcome through the use of more intensive LLT.

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Section: Discussionmentioning

confidence: 99%