CaMK1D signalling in AgRP neurons promotes ghrelin-mediated food intake

Abstract

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Streptococcus salivarius subsp. thermophilus CCFM1312 enhanced mice resilience to activity-based anorexia

“…Many studies have reported that ghrelin mediates appetite and feeding behavior through AgRP/NPY neurons. 34 Our findings suggest that, in ABA mice, altered ghrelin levels in the duodenum may, to some extent, influence or be influenced by brain neuro-metabolism, activating hormonal circuitries to help the body recover from the negative energy balance. However, it is also possible that factors other than peripheral ghrelin contributed to these brain-related outcomes.…”