Campylobacter Enteritis: Clinical and Epidemiologic Features

Blaser, Martin J.; Berkowitz, Ivor; LaForce, F. Marc; Cravens, James; Reller, L. Barth; Wang, W. L.

doi:10.7326/0003-4819-91-2-179

Cited by 500 publications

(228 citation statements)

References 33 publications

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“…Our results and those of Blaser et al (1983) were at variance and several factors such as differences in the strain of mice, differences in their intestinal flora or differences in the virulence of C . jejuni strains used may account for this.…”

Section: Discussionmentioning

confidence: 83%

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Hepatic Lesions in Experimental Campylobacter jejuni Infection of Mice

et al. 1986

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Mice orally infected with Campylobacter jejuni developed focal infiltrative necrotic lesions in the liver, as determined by both histology and liver function tests. The initial histopathological feature was a focal infiltrative lesion in the parenchyma and portal triads. Foci of infiltrative lesions became necrotic between days 30 and 60 post-inoculation (pi.). During this period, portal infiltrates increased in severity. From month 4 pi., focal areas of infiltrative necrosis in the liver parenchyma became extensive. Study of liver function demonstrated mild elevations of transaminases, alkaline phosphatase and lactic dehydrogenase, and also the presence of hypoalbuminaemia. Although histopathological changes of the liver became gradually more marked after day 30 p.i., liver functions of infected mice were most affected at 2 months p.i. The capacity of C. jejuni to induce hepatic lesions seemed to be related to that of organisms to persist in the gall bladder; there was no correlation between biliary carriage in infected mice and positive faecal culture.

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Section: Discussionmentioning

confidence: 83%

“…Also, it has been demonstrated that oral inoculation with C. jejuni can produce disseminated campylobacter infection in mice (Blaser et al, 1983). In the latter study, C. jejuni was isolated early post-inoculation (p.i.)…”

Section: Introductionmentioning

confidence: 99%

Hepatic Lesions in Experimental Campylobacter jejuni Infection of Mice

et al. 1986

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“…Campy-thio: es un medio líquido que consiste en caldo tioglicolato, agar al 0.16% y los inhibidores empleados para el medio sólido (19).…”

Section: Procesamiento De La Muestraunclassified

Presencia de campylobacter jejuni en aves de corral y sus manipuladores

Carmona¹

1985

biomedica

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En una granja procesadora de aves en la ciudad de Cali, donde se sacrifican 12.000 animales diarios, se escogió para buscar Campylobacter jejuni una muestra de 120 pollos tomando como base una prevalencia del 80% y empleando un muestre0 sistemhtico para dar una mayor cobertura teniendo en cuenta que la procedencia de los animales variaba diariamente. El porcentaje de positividad en materia fecal fue de 98.33% (1181120). Con la finalidad de averiguar el grado de higiene empleado en la manipulación de las canales, se frotó la superficie de ellos antes y despues de introducirle las vlsceras que es sabido van dentro del pollo al llegar al consumidor; se encontró que las canales con vlsceras estaban contaminadas en u n 18.33% (11160) mientras que antes de este procedimiento la contaminación tan solo fue del 8.33% (5160). Tambien fueron examinadas 62 personas para buscar en ellas el C. jejuni encontrhndose en 5 (8.06%) la bacteria. A todas las cepas aisladas se les probó la sensibilidad a la eritromicina usando disco de 15 U g observhndose un 100% de sensibilidad a la droga.

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“…4 With the exception of medium S1, which is recommended for holding fecal specimens suspected to contain Campylobacter jejuni, media specifically designed for transport of fecal specimens performed better than conventional media. 3 No viable S. hyodysenteriae could be recovered after holding pure cultures or fecal specimens for 3 days at 25 C and 36 C in medium S1, indicating that the antimicrobial compounds present in this medium inhibited or killed S. hyodysenteriae organisms. This conclusion is further supported by low fecal flora contamination scores in fecal specimens held in this transport medium for more than 3 days (Table 2).…”

Section: Shipping Of Clinical Specimens In Transport Mediamentioning

confidence: 99%

Comparison of Six Commercially Available Transport Media for Maintenance of Serpulina (Treponema) Hyodysenteriae

et al. 1992

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Abstract. Two anaerobic (A1 and A2), 1 selective (S1), and 3 conventional (C1, C2, and C3) transport media formulations were compared for their capacity to maintain the viability of Serpulina (Treponema) hyodysenteriae. Initial experiments compared the recovery of S. hyodysenteriae from pure cultures held in each transport medium for 0.5, 1, 2, 3, 5, and 7 days at -40 C, 4 C, 25 C, and 36 C. Subsequent experiments compared each transport medium for maintenance of S. hyodysenteriae in fecal specimens obtained from experimentally infected pigs after holding for up to 7 days at 25 C. In each experiment, the viability of S. hyodysenteriae in each transport medium incubated at each temperature and for each period was determined by inoculating the transport medium onto either trypticase soy agar with 5% sheep blood or selective BJ agar and incubating at 42 C anaerobically. Viability and fecal flora contamination were evaluated blindly after 2-, 4-, and 6-day incubation periods. At -40 C, recovery of viable S. hyodysenteriae from pure culture did not differ among the transport media from 0.5 to 7 days, and all of the transport media consistently maintained the viability of the spirochetes for 7 days. At 4 C, the anaerobic and selective transport media maintained the viability of pure cultures of S. hyodysenteriae significantly better than did the conventional transport media group at day 7 (P = 0.019). At the same temperature, the anaerobic media maintained viability better than did the conventional media at 5 days (P < 0.042). At 25 C, the anaerobic transport media were significantly better than the conventional transport media at maintaining the viability of pure cultures of the spirochetes at 2, 3, and 5 days (P < 0.018) and were significantly better than the selective medium at 3 days (P = 0.012). At 36 C, the recovery of viable spirochetes was significantly better with the anaerobic transport media than with both the conventional media for days 2-7 (P < 0.006) and the selective medium for days 3-7 (P < 0.049). Fecal specimens held in transport media Al and C1, as a group, had significantly higher viability than those held in the other transport media formulations taken as a group at all incubation times, except 0.5 day (P < 0.0046). Contamination of selective BJ medium by fecal flora was markedly higher after holding fecal specimens in conventional transport media than in anaerobic and selective transport media. In a dilution trial of a pure culture of spirochetes, transport media Al and A2 maintained the viability of 10 8 S. hyodysenteriae for 7 days; however, medium Al was 10-100-fold more effective than medium A2 when lower initial concentrations of spirochetes were sampled. In a dilution trial of a fecal specimen, medium Al maintained the viability of 10 1 spirochetes for 2.5 days compared with 10 3 with medium C1. Overall, media A1 and C1 were the most satisfactory transport media for recovery of viable S. hyodysenteriae from fecal specimens held at 25 C for up to 7 days.Swine dysentery is a highly contagio...

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Campylobacter Enteritis: Clinical and Epidemiologic Features

Cited by 500 publications

References 33 publications

Hepatic Lesions in Experimental Campylobacter jejuni Infection of Mice

Hepatic Lesions in Experimental Campylobacter jejuni Infection of Mice

Presencia de campylobacter jejuni en aves de corral y sus manipuladores

Comparison of Six Commercially Available Transport Media for Maintenance of Serpulina (Treponema) Hyodysenteriae

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