Campylobacter jejuni commonly causes bacterial enteritis but rarely causes extraintestinal infection including bacteremia. We isolated C. jejuni from the blood culture of a 20-year-old man presenting with fever and headache and also from the blood culture of a 23-year-old man suffering abdominal pain and diarrhea. This organism grew in anaerobic culture, showed curved Gram-negative bacilli by Gram stain, and was identified by matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS).