Can augmentation index be used as an accurate tool in the diagnosis of peripheral obstructive arterial disease?

Coyle, P.; Duff, Gerald; Gavín, Olga; Moloney, M.; Burke, P.; Kavanagh, Eamon G.; Grace, Pierce A.

doi:10.1007/s11845-011-0796-z

Cited by 1 publication

(2 citation statements)

References 11 publications

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“…RAI used to be employed as a reliable indicator of peripheral vascular health. RAI is a reliable measure of arterial stiffness in people suffering from diabetes mellitus and in young patients with asymptomatic vascular disease, suggesting an important association with vascular function [13]. In the present study, RAI was positively correlated with AACI and carotid artery IMT, which showed that vessel flexibility was coincident with structural damage.…”

Section: Discussionsupporting

confidence: 66%

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Radial augmentation index may be an effective predictor of vascular calcification in patients on peritoneal dialysis

Yang

Cui

et al. 2020

Renal Failure

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Vascular calcification (VC) is an important promoter of cardiovascular disease (CVD) in patients undergoing peritoneal dialysis (PD). Several indices can be used to evaluate VC, including the abdominal aortic calcification index (AACI) and carotid artery intima-media thickness (IMT); however, simpler and lesser expensive predictors, such as the radial augmentation index (RAI), should be investigated. A total of 101 patients undergoing PD were recruited to measure RAI, AACI, and carotid artery IMT and perform echocardiography. Fifty healthy controls (HCs) were recruited to undergo RAI measurement. RAI in patients undergoing PD was significantly higher than the RAI in HCs (86.25%±8.39% vs. 76.05%±9.81%, p < 0.05). Patients undergoing PD and who suffer with diabetic mellitus, hypertension, and CVD had more severe VC than those without the abovementioned diseases. In patients with PD, RAI was positively correlated with AACI (r ¼ 0.671, p < 0.05) and carotid artery IMT (r ¼ 0.596, p < 0.05). RAI was positively correlated with left ventricular enddiastolic dimensions (LVDd; r ¼ 0.678, p < 0.05), left ventricular mass index (r ¼ 0.595, p < 0.05), and negatively correlated with early-diastolic mitral inflow velocity/late-diastolic mitral inflow velocity (r ¼ À0.342, p < 0.05) and left ventricular ejection fraction (r¼ À0.497, p < 0.05). Multiple linear regression analysis showed that RAI was associated with AACI, LVDd, age, and serum phosphate (p < 0.05). RAI might be an effective predictor of VC and cardiac structural/functional abnormalities in patients undergoing PD.

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Section: Discussionsupporting

confidence: 66%

“…In addition, there was a significant increase in RAI in patients with peripheral obstructive vascular disease compared with healthy individuals. RAI appears to be an essential indicator of peripheral obstructive arterial disease [13]. The RAI is a useful and readily obtainable parameter for vascular aging.…”

Section: Introductionmentioning

confidence: 99%

Radial augmentation index may be an effective predictor of vascular calcification in patients on peritoneal dialysis

Yang

Cui

et al. 2020

Renal Failure

View full text Add to dashboard Cite

show abstract

Can augmentation index be used as an accurate tool in the diagnosis of peripheral obstructive arterial disease?

Abstract: The augmentation index appears be a significant indicator of cardiovascular disease and may be a useful tool in the diagnosis of vascular pathology.

Cited by 1 publication

References 11 publications

Radial augmentation index may be an effective predictor of vascular calcification in patients on peritoneal dialysis

Radial augmentation index may be an effective predictor of vascular calcification in patients on peritoneal dialysis

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