Can Cannabinoids Suppress the Cytokines Cascade in Patients with Coronavirus Disease COVID-19? A Mini-Review

Abstract

: Coronavirus disease-2019 (COVID-19), caused by SARS-CoV-2, has started in Wuhan China in December 2019 and becomes a global pandemic. According to WHO, more than fourteen million cases are reported and thousands of casualties worldwide (until July 18, 2020) . Most of the COVID-19 patients have symptoms such as fever, feeling tired, dry cough. Some people may also experience aches and pains, nasal congestion, a runny nose, and diarrhea. So far doctors have been using treatment to relieve symptoms and give patients' immune systems time to regain control of this virus. Many studies have highlighted the important role of cytokine cascades in the death rate in COVID-19 patients. Therefore, inhibition of this phenomenon has become a very important target in the clinical management of this disease. With this idea, in this minireview, we will focus on the potential role of cannabinoids in the suppression of cytokines cascades in patients with COVID-19 and their importance in the clinical management of this disease.