Can coffee consumption lower the risk of Alzheimer’s disease and Parkinson’s disease? A literature review

Abstract

In light of the fact that the number of elderly citizens in society is steadily increasing, the search for dietary factors which might prolong mental agility is growing in significance. Coffee, together with its main ingredient, caffeine, has been the focus of much attention from various researchers, as data on its beneficial effects on human health continue to accumulate. Most reports indicate that moderate coffee consumption may in fact lower the risk for common neurodegenerative conditions, i.e. Alzheimer’s and Parkinson’s diseases. Regardless, due to their complex pathogenesis as well as methodology of scientific research, the exact impact of coffee consumption remains to be fully elucidated. At present, it seems safe to inform the general public that coffee drinkers need not fear for their health. Possibly, in the future experts will recommend drinking coffee not only to satisfy individual taste preferences but also to decrease age-related mental deterioration.

Stool Immune Profiles Evince Gastrointestinal Inflammation in Parkinson's Disease

“…We observed reduced current coffee intake in our cohort of PD patients as well as reduced current alcohol consumption, in agreement with previous reports. Although coffee and caffeine are known to have potent neuroprotective and anti-inflammatory properties, 57 this study found only a minimal effect of alcohol and coffee consumption on levels of stool immune mediators, with coffee intake inversely associated with IL-6 levels. We found no differences between PD patients and controls in smoking history, but we did observe that having smoked at least 100 cigarettes reduced levels of multiple immune factors in stool.…”

“…Coffee and alcohol consumption and smoking are all reportedly reduced in PD patients, but whether these findings indicate protective effects of these practices, disease‐associated suppression of psychological reward mechanisms, or simply reduced fluid intake because of dysphagia in advanced disease remains undetermined. We observed reduced current coffee intake in our cohort of PD patients as well as reduced current alcohol consumption, in agreement with previous reports.…”

Review on Health Benefit and Risk of Coffee Consumption

“…it mainly by the death of dopamine-producing neurons in our brain [86][87][88][89][90][91] Coffee consumption protects against 65 or more aged people from Alzheimer's disease and dementia. It lower 65% risk of Alzheimer's disease…”

“…The neurodegenerative disease most common in old people over 65 years of age and above [64,89,[91][92][93] [32, 61,[94][95][96][97][98][99][100][101] Coffee consumption can lower about 26% probability of colorectal cancer, especially distal colon cancer. It is known as a healthy beverage for the prevention of colorectal cancer.…”

Impact of Tea and Coffee Consumption on Cognitive Performance: An fNIRS and EDA Study

“…This indicates that moderate consumption of caffeine can affect cognition [8]. Coffee and tea consumption has been studied extensively to determine the long-term effects of consumption and the associations with numerous diseases such as diabetes, hypertension, Alzheimer's disease, and dementia [9][10][11][12]. Most previous studies have also only used behavioral performance and self-reported measures to understand the effects of consumption on cognition.…”