Can dog allergen alone, if combined with indoor pollution, be responsible for asthma in children?

Liccardi, Gennaro; Annesi‐Maesano, Isabella; Salzillo, Antonello; D’Amato, Gennaro

doi:10.1183/09031936.00057311

Cited by 2 publications

(1 citation statement)

References 4 publications

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“…A letter commenting these results reported that in 'real life' it is unrealistic to separate the role of dog allergens from that of other allergens commonly found indoors. The importance of both cat and dog allergens as risk factors for induction of allergic sensitization and bronchial asthma is not limited to shared indoor environments: in vitro studies have shown cross-reactivity between these allergens [115].…”

Section: Interaction Between Air Pollution and Biological Allergensmentioning

confidence: 99%

Allergy and asthma: Effects of the exposure to particulate matter and biological allergens

Baldacci

Maio

Cerrai

et al. 2015

Respiratory Medicine

Self Cite

228

137

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The prevalence of asthma and allergies including atopy has increased during the past decades, particularly in westernized countries. The rapid rise in the prevalence of such diseases cannot be explained by genetic factors alone. Rapid urbanization and industrialization throughout the world have increased air pollution and population exposures, so that most epidemiologic studies are focusing on possible links between air pollution and respiratory diseases. Furthermore, a growing body of evidence shows that chemical air pollution may interact with airborne allergens enhancing the risk of atopic sensitization and exacerbation of symptoms in sensitized subjects. These phenomena are supported by current in vitro and animal studies showing that the combined exposure to air pollutants and allergens may have a synergistic or additive effect on asthma and allergies, although there is an insufficient evidence about this link at the population level. Further research is needed in order to elucidate the mechanisms by which pollutants and biological allergens induce damage in exposed subjects. The abatement of the main risk factors for asthma and allergic diseases may achieve huge health benefits. Thus, it is important to raise awareness of respiratory allergies as serious chronic diseases which place a heavy burden on patients and on society as a whole.

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Section: Interaction Between Air Pollution and Biological Allergensmentioning

confidence: 99%

Allergy and asthma: Effects of the exposure to particulate matter and biological allergens

Baldacci

Maio

Cerrai

et al. 2015

Respiratory Medicine

Self Cite

228

137

View full text Add to dashboard Cite

show abstract

Pets and related allergens modify the association between early life DEHP exposure and respiratory outcomes in children

Zhang,

Dai,

Lou

et al. 2025

Environmental Research

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Can dog allergen alone, if combined with indoor pollution, be responsible for asthma in children?

Cited by 2 publications

References 4 publications

Allergy and asthma: Effects of the exposure to particulate matter and biological allergens

Allergy and asthma: Effects of the exposure to particulate matter and biological allergens

Pets and related allergens modify the association between early life DEHP exposure and respiratory outcomes in children

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