Can emotional stress trigger the onset of epilepsy?

Gélisse, Philippe; Genton, Pierre; Coubes, Philippe; Tang, Ngoc Phuong Loc; Crespel, Arielle

doi:10.1016/j.yebeh.2015.05.010

Cited by 26 publications

(20 citation statements)

References 16 publications

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“…In reality, this is not entirely new as the role of the hypothalamic-pituitary-adrenal (HPA) axis in depression is well established. However, it is now evident that pretreatment with corticosterone accelerates the kindling process in rats [22] and this would be in keeping with the emerging literature on the potential role of stress in epilepsy [23]*** not only as a precipitant factor but also as a potential causative one [24]. The disruption in GABA and glutamate neurotransmissions used to be a classic finding in epilepsy but cumulative data are now showing similar findings in depression through a HPA mediated mechanism.…”

Section: Depression As a Premorbid Conditionmentioning

confidence: 67%

Depression in epilepsy

Mula

2017

Current Opinion in Neurology

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Section: Depression As a Premorbid Conditionmentioning

confidence: 67%

Depression in epilepsy

Mula

2017

Current Opinion in Neurology

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“…18 Other available studies to date have been small and taken from selected secondary care populations without control populations. 19,20 The experience of stressful life events has been studied in relation to seizure frequency, 21 epilepsy onset, 22 and in studies comparing people with epilepsy with people with nonepileptic attack disorder. 19,[23][24][25] Stressful life events have also been proposed to have an epileptogenic effect, in addition to being associated with psychopathology.…”

mentioning

confidence: 99%

Discrimination, domestic violence, abuse, and other adverse life events in people with epilepsy: Population‐based study to assess the burden of these events and their contribution to psychopathology

et al. 2016

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General rightsThis document is made available in accordance with publisher policies. Please cite only the published version using the reference above. Full terms of use are available: http://www.bristol.ac.uk/pure/about/ebr-terms Discrimination, domestic violence, physical and sexual abuse, and other stressful life events were assessed using computerised self-completion and a face to face interview respectively. Results:People with epilepsy were seven-fold more likely to have reported experiencing discrimination due to health problems (adjusted OR=7.1; 95% CI=3·1 -16.3), than the general population without epilepsy. This estimate was substantially greater in people with epilepsy than for people with other chronic conditions. People with epilepsy also had greater odds of experiencing domestic violence and sexual abuse than the general population, although these associations were also found in people with other chronic conditions. There was less evidence of an association between epilepsy and a history of physical abuse or having a greater burden of other stressful life events. In exploratory analyses, assuming they lie on the causal pathway, discrimination, domestic violence and sexual abuse explained 42.7% of the total effect of the relationship between epilepsy and depression or anxiety disorders.Significance: People with epilepsy can face a range of psychosocial adversities and extensively report feeling discriminated against as compared to the general population. In addition, if confirmed in longitudinal studies, the results suggest that these psychosocial adversities may have a significant role in the development of psychiatric comorbidity and may be targets for future interventions.

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“…Other researchers have shown a high correlation between stress, sleep deprivation and fatigue. [27] According to the study results of Sorour et al (2014), [28] the application of the progressive relaxation technique was associated with a significant decrement in the level of stress among epileptic adolescents. The intervention was successful in reducing seizures triggering factors, the results revealed statistically significant changes in stress scale, with a median post-pre total difference of -0.3 (p < .001).…”

Section: Discussionmentioning

confidence: 97%

Effect of designing a nursing educational protocol on frequency of epileptic attacks

Mohammed

Mohammed²,

Hassan³

2018

JNEP

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Background and objective: Educating the epileptic patient represents a critical part of quality care and is considered a therapeutic outcome for those patients. This study aimed to determine epileptic patients' knowledge regarding the disease and frequency of seizure attacks prior to the implementation of the educational protocol and to evaluate the effect of an educational protocol on epileptic patient's knowledge and frequency of seizure attacks.Methods: Design: A quasi-experimental (pre-posttest) design was submit to meet the aim of the study. Patients: Sixty convenient male and female adult seizure patients were their age ranged between 18-64 years. Setting: This study was carried out in Neurological department and neurology out-patient clinic at Minia University Hospital. Tools of data collection: Four tools were utilized; Pre/posttest questionnaire sheet, Perceived Stress Scale, Epworth Sleepiness Scale, and patient teaching booklet.Results: About 86.7% of the study sample has an unsatisfactory level of knowledge about seizures and 13.3% have satisfactory knowledge about seizures before the implementation of the protocol. While in posttest II it was noticed that 90.0% have satisfactory knowledge about seizures. There was a high positive significant correlation between perceived stress scale and frequency of attacks among the study subjects.Conclusions: An improvement in seizure patients’ knowledge after the implementation of the educational protocol. An improvement in patient’s knowledge positively reflected on minimization and control frequency of seizure attacks. Recommendation: An educational and training protocol should be planned in a continuous manner and offered on regular basis to seizure patients.

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Can emotional stress trigger the onset of epilepsy?

Cited by 26 publications

References 16 publications

Depression in epilepsy

Depression in epilepsy

Discrimination, domestic violence, abuse, and other adverse life events in people with epilepsy: Population‐based study to assess the burden of these events and their contribution to psychopathology

Effect of designing a nursing educational protocol on frequency of epileptic attacks

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