Can Fetal Heart Lie? Intrapartum CTG Changes in COVID-19 Mothers

Farhan, Fatin Shallal; Nori, Wassan; Kadir, Israa Talib Abd Al; Hameed, Ban Hadi

doi:10.1007/s13224-022-01663-6

Cited by 15 publications

(12 citation statements)

References 31 publications

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“…Despite the low rate of vertical transmission, poor neonatal outcomes such as intrauterine fetal growth restriction or fetal distress was more frequently found in case of maternal COVID-19 disease [ 51 , 52 , 53 ]. While poor maternal oxygenation could be blamed for this issue, most studies point to the abnormal functionality of the fetoplacental unit [ 54 ].…”

Section: Discussionmentioning

confidence: 99%

Pregnancy Outcomes in SARS-CoV-2-Positive Patients: A 20-Month Retrospective Analysis of Delivery Cases

et al. 2023

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Background and Objectives: The SARS-CoV-2 infection brings supplemental risks for pregnant women. Due to controversial hesitancy, their vaccination rate was lower in 2021 compared to the general population. In addition, access to maternal care was reduced during the pandemic. We conducted a retrospective cross-sectional analysis of the health records data over 20 months (1 April 2020 to 20 November 2021) aiming to explore the outcomes in SARS-CoV-2-positive cases referred for delivery to a tertiary public hospital in Western Romania. Materials and Methods: Women with SARS-CoV-2 infection diagnosed for the first time at the moment of birth who delivered singletons after 24 weeks of gestation, and had a clear immunization status were included in the analysis. Results: Out of the 97 patients included in the study, 35 (36%) had undergone ARN-based vaccination. Five cases of maternal death were recorded (all unvaccinated). Our retrospective exploratory analysis showed that the presence of COVID-19 symptoms in the SARS-CoV-2-positive patients made a significant impact on the delivery hospitalization, with a median hospital stay increase from 5 to 9 days (Mann–Whitney test, p = 0.014): longer hospitalization was recorded in the symptomatic cases irrespective of their vaccination status. No other adverse outcomes, such as gestational age at delivery, C-section rate, 5 min Apgar index, or birth weight were associated with the presence of symptoms. Conclusions: Our clinic maintained safe maternal care for the COVID-19 patients during the analyzed period. Vaccination of the expectant women was beneficial in SARS-CoV-2-positive patients by lowering the risk of COVID-19 symptoms, with subsequent implications on the newborns’ health and maternal attachment.

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Section: Discussionmentioning

confidence: 99%

Pregnancy Outcomes in SARS-CoV-2-Positive Patients: A 20-Month Retrospective Analysis of Delivery Cases

et al. 2023

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“…We were more interested in the link of StAR gene expression to IVF parameters and outcomes irrespective of PCOS phenotype. Another drawback is a small sample size, owing to the difficulty in obtaining the sample, the strict inclusion criteria we set for enrolment, and the COVID-19 pandemic [44].…”

Section: Tabatabaie Et Al Study Confirmed the Presence Of Star Gene I...mentioning

confidence: 99%

The effect of adipose tissue StAR gene expression on ICSI among Polycystic Ovarian Syndrome cases and matched controls: a case-control study

Helmi¹,

Nori²

2024

Ital J Gynaecol Obstet

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Objective. steroidogenesis is vital for reproduction and fertility; it is governed by the acute regulatory protein gene (StAR). Earlier work discussed a different StAR expression in the adipose tissue (AT) of pregnant polycystic ovarian syndrome (PCOS) women. This study examined the correlation of StAR expression levels in AT of PCOS women to various parameters of intracytoplasmic sperm injection (ICSI) compared to those without. Patients and methods.A case-control study recruited 40 infertile women who had successful ICSI cycles into 2 groups: 20/40 cases and 20/40 non-PCOS cases; both groups were age and body mass index-matched for scheduled elective cesarean section. A sample of anterior abdominal wall AT was taken for a real-time PCR StAR gene expression. ICSI parameters, including hormonal, ultrasonic, stimulation drug doses and duration, and the outcome, were all retrospectively recorded and correlated with StAR gene expression.Results. StAR gene folding was higher among PCOS-pregnant women (2.545 ±1.58 vs. 1.00 ±0.0), P-value< 0.023. estradiol hormone was correlated to StAR gene; -0.39, P<0.05. The total doses of recombinant follicle-stimulating hormone and human menopausal gonadotropin had significant correlations to StAR gene r= (-0.39, 0.60), P-value of (0.049, 0.005), respectively.Conclusions. The significant association of StAR gene expression with stimulation drug doses suggests a clinical application, as it can reduce ovarian hyperstimulation syndrome and overall expense, which makes ICSI safer and more accessible to infertile couples. Women with PCOS present challenges in ICSI, and thus careful balance must be adjusted.

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“…The Corona Virus Infectious Disease(COVID)-19 pandemic has had a detrimental effect on fetal-maternal outcomes[ 26 ]. Celik et al [ 27 ] discovered a considerable change in Vm in affected cases.…”

Section: To the Editormentioning

confidence: 99%

Vaginal microbes confounders and implications on women's health

Nori¹,

H-Hameed²

2023

World J Clin Cases

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The vagina has diverse vaginal microbes (Vm). A disturbance in the delicate balance maintained in Vm is linked to women's obstetrical and reproductive tract problems. Vaginal microbes play an essential role in protecting the health of the female reproductive tract by alleviating gynecological infection. However, Vm profiling has many confounders that need to be addressed during sampling, including age, race, pregnancy, medical illness, and smoking. Vm profiling improves reproduction odds, may serve as a marker for genital malignancies and have a therapeutic application in menopausal women and women with cervical cancers.

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Can Fetal Heart Lie? Intrapartum CTG Changes in COVID-19 Mothers

Cited by 15 publications

References 31 publications

Pregnancy Outcomes in SARS-CoV-2-Positive Patients: A 20-Month Retrospective Analysis of Delivery Cases

Pregnancy Outcomes in SARS-CoV-2-Positive Patients: A 20-Month Retrospective Analysis of Delivery Cases

The effect of adipose tissue StAR gene expression on ICSI among Polycystic Ovarian Syndrome cases and matched controls: a case-control study

Vaginal microbes confounders and implications on women's health

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