Can Lifestyle Factors of Diabetes Mellitus Patients Affect Their Fertility?

Aboua, Yapo Guillaume; Oguntibeju, Oluwafemi Omoniyi; Plessis, Stefan S. du

doi:10.5772/47838

Cited by 4 publications

(3 citation statements)

References 105 publications

(109 reference statements)

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“…Estas intervenciones, sin embargo, podrían ser difíciles de aplicar debido a las dificultades en la adhesión a estos cambios durante un prolongado período. La terapia con medicamentos puede ser apropiada cuando estas intervenciones son ineficaces o inviables 101 .…”

Section: ) Drogas Para El Tratamiento De La Dm Y Su Impacto Sobre Launclassified

“…Diversos estudios han demostrado que el tratamiento con metformina en ratas con disfunción eréctil e IR causó un mayor síntesis de NO a nivel de las arterias cavernosas y una mejora en la disfunción 101,113 . A su vez se comprobó en humanos que el tratamiento con metformina en pacientes con disfunción eréctil y mala respuesta al sildenafil reduce la IR y mejora la función eréctil.…”

Section: ) Drogas Para El Tratamiento De La Dm Y Su Impacto Sobre Launclassified

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Trastornos De La Fertilidad en El Hombre Con Diabetes Tipo 1 Y 21

Pomares

Burruchaga²,

Ávila³

et al. 2014

Rev. Soc. Argent. Diabetes

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La diabetes mellitus (DM) es una de las mayores amenazas para la salud pública en las sociedades modernas. Si bien durante varios años se sugirió que la DM no tenía efecto significativo en la función reproductiva masculina, esta visión fue cambiando. La creciente incidencia de la DM a nivel mundial afectará a cada vez más hombres y de menor edad, y por lo tanto podría afectar su potencial reproductivo.

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Section: ) Drogas Para El Tratamiento De La Dm Y Su Impacto Sobre Launclassified

Trastornos De La Fertilidad en El Hombre Con Diabetes Tipo 1 Y 21

Pomares

Burruchaga²,

Ávila³

et al. 2014

Rev. Soc. Argent. Diabetes

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“…In the context of males, a man is said to be infertile if he is unable to impregnate his partner after one year of unprotected intercourse (Singh et al, 2014). This condition may result from a number of factors including hormonal imbalances, genetic defects, chemicals, and toxins exposure reproductive anatomical and morphological abnormalities, reactive oxygen species, and smoking (Aboua et al, 2013; Singh et al, 2014).…”

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confidence: 99%

Effect of Hydromethanolic Seed Extract of Garcinia Kola on Male Reproductive Hormones

Harry

2022

Preprint

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Reproduction is central to the continued existence of mankind on earth, while infertility presents both a social and a public health concern, with male factor infertility present in 20% to 50% of all cases of infertility among couples. As part of the solution for male fertility disorders, drugs including those that are plant-based are being employed to address such issues. Hence, this study was focused on the effect of the administration of hydro-methanol seed extract of G. kola on the reproductive hormone of adult male Wistar rats. The plant material was procured, identified, and extracted while a total of 36 adult male rats were procured and distributed equally into three groups which were subdivided into two. Animals in group 1 served as the control while groups 2 and 3 served as the extract-treated groups which received 100 and 200 mg/kg BW of the extract respectively. Those in subgroups A and B were treated for 14 and 30 days respectively after which the animals were sacrificed and the blood collected via cardiac puncture into the appropriate bottles for hormonal profile assay. The result showed that the administration of the extract resulted in a reduction in the level of FSH and LH but increased the level of Testosterone, with a significant increase recorded in the 200 mg/kg group, while the level of prolactin was increased in the 100 mg/kg group but decreased in the 200mg/kg group. Hence, Garcinia kola might not be the best solution to aid fertility in males.

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