Can Neutrophil-to-Lymphocyte or Platelet-to-Lymphocyte Ratio Be Used to Predict Postoperative Nausea and Vomiting in Breast Reduction?

Karaca, Onur; Doğan, Güvenç

doi:10.7759/cureus.7237

Cited by 8 publications

(23 citation statements)

References 20 publications

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“…While the cut-off values determined for NLR in predicting PONV in previous studies were generally around 2 [1,2,21], this value was found to be 3.01 in the preoperative period and 7.13 in the postoperative period in our study. This difference may be related to the stress response of the patients and the inflammatory response to chest tube application in pneumothorax cases.…”

Section: Discussioncontrasting

confidence: 70%

“…The confounder effect was controlled using the Propensity Score Matching (PSM) analysis in order to distribute the case-control groups similarly in terms of statistical comparisons. Prior to the study, the confounder between the case-control groups was matched in terms of the continuous variables, age, gender, body mass index (BMI), ASA scores, smoking, and additional diseases [ 1 ]. Propensity scores were predicted using the combined estimator (ensemble learning: a combination of logistic regression and machine learning algorithms) developed by Demir et al (2019) [ 15 ].…”

Section: Methodsmentioning

confidence: 99%

“…Postoperative nausea and vomiting (PONV) is one of the most common complications defined as nausea and vomiting that develops within the postoperative 24 hours [ 1 , 2 ]. PONV is associated with negative effects ranging from pain at the suture line to postoperative morbidity, as well as ongoing anxiety in patients after surgery [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

“…The prevalence of PONV in surgical cases performed under general anesthesia may be between 30% and 80%. It is one of the most common and important problems that also reduce patient satisfaction [ 1 ]. In the literature, it is claimed that many demographic factors associated with PONV risk, as well as surgery type, anesthesia characteristics, anesthesia duration, postoperative opioid use, IV anesthetics, and inflammation, increase this risk [ 1 , 2 ].…”

Section: Introductionmentioning

confidence: 99%

“…In the literature, many factors such as demographic characteristics of patients, duration of surgery, type of surgery, anesthetic and analgesic methods, and opioid use determine the incidence of PONV [ 13 ]. In addition, there are recent studies showing that inflammatory markers such as neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) can predict PONV [ 1 , 2 ].…”

Section: Introductionmentioning

confidence: 99%

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Parameters Affecting Nausea and Vomiting After Thoracoscopic Wedge Resection in Patients With Pneumothorax

Zengin¹,

Sazak²,

Baldemir³

et al. 2021

Cureus

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Background: Postoperative nausea and vomiting (PONV) is one of the complications that can occur frequently in the first 24 hours postoperatively. We aimed to investigate the parameters that could predict PONV in patients who underwent thoracoscopic wedge resection for pneumothorax.Materials and Methods: After obtaining the approval of the ethics committee (ID: 2012-KEAK-15/2358, Date: 14.09.2021), the records of patients who underwent elective video-assisted thoracic surgery (VATS) between January 2018 and June 2021 were analyzed retrospectively. The patients who underwent elective thoracoscopic wedge resection for pneumothorax, who were between the ages of 18-65, American Society of Anesthesiologists (ASA) I-III, and whose body mass index (BMI) was between 18-30 kg/m 2 were included in the study. However, patients who received a blood transfusion or used antiemetics, anticholinergic drugs, and analgesics continuously were not included. In addition, patients with a history of chronic pain were not included in the study. The patients were divided into two groups, the PONV group (Group 1) and the control group (Group 2). The PONV incidence, visual analog scale (VAS) scores, 24-hour morphine consumption, additional analgesic requirement, neutrophil/lymphocyte ratios (NLR), and platelet/lymphocyte ratios (PLR) were evaluated.Results: The groups were similar in terms of demographic data (p > 0.05). Additional analgesic requirement and 24-hour morphine consumption were significantly higher in the PONV group (p: 0.005, p < 0.001, respectively). Preoperative NLR (p < 0.001), postoperative NLR (p < 0.001), preoperative PLR (p < 0.022), the VAS scores of the first hour (p: 0.004), and 24 th hour (p < 0.001) were statistically significantly higher in the PONV group compared to the control group.Conclusions: NLR parameters can be effective with high sensitivity and specificity in predicting PONV during the preoperative and postoperative period. Besides, preoperative PLR may also be effective in predicting PONV. A treatment that can be planned according to these parameters may play a key role in preventing PONV. In addition, efficient perioperative analgesia management may be effective in reducing PONV by limiting the emetogenic analgesics.

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Section: Discussioncontrasting

confidence: 70%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Parameters Affecting Nausea and Vomiting After Thoracoscopic Wedge Resection in Patients With Pneumothorax

Zengin¹,

Sazak²,

Baldemir³

et al. 2021

Cureus

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The risk factors of postoperative nausea and vomiting in patients undergoing laparoscopic sleeve gastrectomy and laparoscopic distal gastrectomy: a propensity score matching analysis

Chen

ZhengYao

et al. 2023

Sci Rep

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Postoperative nausea and vomiting (PONV) is a common side effect after laparoscopic surgery. The aim of the study is to investigate the variables that could predict PONV in patients who underwent laparoscopic gastrectomy. We divided patients who underwent laparoscopic gastrectomy into PONV and No-PONV groups. Propensity score matching (PSM) was applied to adjust confounding factors for further validation, and ordinal logistic regression analysis was used to identify predictors for PONV. In the ordinal logistic regression analysis, the preoperative neutrophil-to-lymphocyte ratio (NLR) (odds ratio [OR]: 3.19, 95% confidence interval [CI]: 1.38–7.38; p < 0.01) was identified as an independent risk factor for the presence of PONV and a predictor of the severity of PONV (OR: 3.44, 95% CI: 1.67–5.20; p < 0.01) in 94 PSM patients. Besides, NLR was positively correlated with the PONV score (r = 0.534, p < 0.001). In the receiver-operating characteristic (ROC) curve analysis, an NLR with an optimal cutoff value of 1.59 predicted severe PONV with a sensitivity of 72% and specificity of 81%. The NLR was an independent risk factor for the presence of PONV, and a high NLR tends to be positively associated with the severity of PONV after laparoscopic gastrectomy.

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Polimorfismo genético associado com a ocorrência de náuseas e vômitos pós-operatórios (NVPO) em pacientes submetidos a cirurgias oncológicas

Slullitel

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pelo exemplo de capacidade técnica, dedicação, perseverança e estímulos contínuos em busca de conhecimentos e resultados. Ao Dr. Thiago Grigio, pelo grande auxílio na coleta de dados, execução e condução deste trabalho. Ao Prof. Dr. Roger Chamas, pelo incentivo inicial, confiança na concepção e execução deste projeto. RESUMO Slullitel A. Polimorfismo genético associado com a ocorrência de náuseas e vômitos pósoperatórios (NVPO) em pacientes submetidos a cirurgias oncológicas [tese].

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Can Neutrophil-to-Lymphocyte or Platelet-to-Lymphocyte Ratio Be Used to Predict Postoperative Nausea and Vomiting in Breast Reduction?

Cited by 8 publications

References 20 publications

Parameters Affecting Nausea and Vomiting After Thoracoscopic Wedge Resection in Patients With Pneumothorax

Parameters Affecting Nausea and Vomiting After Thoracoscopic Wedge Resection in Patients With Pneumothorax

The risk factors of postoperative nausea and vomiting in patients undergoing laparoscopic sleeve gastrectomy and laparoscopic distal gastrectomy: a propensity score matching analysis

Polimorfismo genético associado com a ocorrência de náuseas e vômitos pós-operatórios (NVPO) em pacientes submetidos a cirurgias oncológicas

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