Can Nutritional Intervention for Obesity and Comorbidities Slow Down Age-Related Hearing Impairment?

Tang, Ting-Hsuan; Hwang, Juen-Haur; Yang, Ting‐Hua; Hsu, Chuan‐Jen; Wu, Chen‐Chi; Liu, Tien‐Chen

doi:10.3390/nu11071668

Cited by 13 publications

(8 citation statements)

References 81 publications

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“…Furthermore, it has been found that hearing loss causes an increase in oxidative stress, an increase in the inflammatory state, sedentary lifestyle, and lack of physical activity [28]. The participation of intermediary factors should also be mentioned, such as atherosclerosis, which can be found in hypertension and reduce blood flow to the cochlea by hardening or constricting the internal auditory artery [29].…”

Section: Interpretation Of Resultsmentioning

confidence: 99%

Hearing Loss due to Noise Exposure and its Relationship with Hypertension in Peruvian Workers

Saldaña

Torres-Malca

Zuzunaga-Montoya

et al. 2022

ijsmr

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Introduction: Noise-induced hearing loss has been implicated in the genesis of several chronic conditions; however, its behavior concerning hypertension still raises doubts about it. Objective: to determine the association between hearing loss due to exposure to noise and the presence of hypertension in a sample of Peruvian workers. Methods: Cross-sectional analytical study. Secondary analysis of the occupational database of a Medical center in Lima, Peru. hypertension was measured by self-report and clinical method. Hearing loss was classified as none, mild, moderate and severe. For the regression analysis, Poisson was performed with robust variance, obtaining crude (PRc) and adjusted (PRa) prevalence ratios. Results: We worked with a total of 1987 participants. The prevalence of hypertension was 15.40% and hearing loss was 36.39%. For the multivariate regression analysis, a statistically significant association with hypertension was found in those with mild hearing loss (PRa=1.52; CI95% 1.06–2.10), moderate (PRa=2.70; CI95% 1,93–3.76) and severe (PRa=3.82; 95% CI 2.56–5.96), compared to those without hearing loss. Conclusions: Hearing loss due to exposure to occupational noise was associated with the presence of hypertension. Although this study is only a first overview of the relationship that both variables could have, it is recommended to continue promoting policies and awareness campaigns to prevent hearing loss in workers, and thus avoid complications related to it in the long term.

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Section: Interpretation Of Resultsmentioning

confidence: 99%

Hearing Loss due to Noise Exposure and its Relationship with Hypertension in Peruvian Workers

Saldaña

Torres-Malca

Zuzunaga-Montoya

et al. 2022

ijsmr

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“…Postmitotic HCs and SGNs are particularly susceptible to noise exposure, ototoxic substances, and oxidative damage. Blood vessels in the stria vascularis deliver nutrients such as oxygen and glucose to the cochlea [87] . The microcirculation of the cochlea includes that of the cochlear spiral organ region, stria vascularis, and vestibular organs.…”

Section: Cochlear Microcirculation and Inflammationmentioning

confidence: 99%

“…Blood vessels in the stria vascularis deliver nutrients such as oxygen and glucose to the cochlea. [87] The microcirculation of the cochlea includes that of the cochlear spiral organ region, stria vascularis, and TA B L E 1 Differences between the BBB and BLB.…”

Section: Interactions Between Cochlear Inflammatory Response and Immu...mentioning

confidence: 99%

Understanding the role of inflammation in sensorineural hearing loss: Current goals and future prospects

Li,

Chen,

Lin

et al. 2023

Brain-X

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Sensorineural hearing loss (SNHL) is a common otologic condition caused by damage to hair cells and spiral ganglion neurons that affects transmission pathways. Most of these cells cannot be regenerated, and there has been no breakthrough in regeneration techniques for inner ear cells. SNHL has a high incidence rate and can cause a variety of clinical symptoms, greatly impacting people's daily lives. With limited clinical treatments, the search for critical targets is urgent. Studies have shown that inflammation is prevalent in the pathogenesis of SNHL and plays a significant role in it. Inflammation is a normal body defense response, and a systemic anti‐inflammatory approach is undesirable. It is crucial for us to identify potential targets of inflammation in SNHL and take measures specifically targeting those targets with minimal systemic impact. This paper firstly describes the role of inflammation in various types of SNHL and then provides an overview of the interactions between inflammation and cochlear immunity, cochlear microcirculation, vascular spasm, and glutamate metabolism and finally comprehensively examines the feasibility of targets in these interactions. This paper is expected to facilitate the development of targeted anti‐inflammation for SNHL and provide strategies and approaches for treating clinical SNHL.

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“…Our previous clinical cohort study highlighted the protective role of adiponectin against ARHL development [67]. The interaction between adiponectin and its type 1 receptor in the cochlea may exhibit protective effects against hair cell apoptosis [68,69]. Low-fat diets, wherein 30% or less of the calories are derived from fat, may also protect against ARHL.…”

Section: Low Fat and Low Cholesterol Dietmentioning

confidence: 99%

Effects of Diet and Lifestyle on Audio-Vestibular Dysfunction in the Elderly: A Literature Review

Chen

Tan

et al. 2022

Nutrients

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Background: The world’s age-related health concerns continue to rise. Audio-vestibular disorders, such as hearing loss, tinnitus, and vertigo, are common complaints in the elderly and are associated with social and public health burdens. Various preventative measures can ease their impact, including healthy food consumption, nutritional supplementation, and lifestyle modification. We aim to provide a comprehensive summary of current possible strategies for preventing the age-related audio-vestibular dysfunction. Methods: A PubMed, Embase, and Cochrane review databases search was conducted to identify the relationship between diet, lifestyle, and audio-vestibular dysfunction. “Diet,” “nutritional supplement,” “lifestyle,” “exercise,” “physical activity,” “tinnitus,” “vertigo” and “age-related hearing loss” were used as keywords. Results: Audio-vestibular dysfunction develops and progresses as a result of age-related inflammation and oxidative stress. Diets with anti-inflammatory and antioxidant effects have been proposed to alleviate this illness. A high-fat diet may induce oxidative stress and low protein intake is associated with hearing discomfort in the elderly. Increased carbohydrate and sugar intake positively correlate with the incidence of audio-vestibular dysfunction, whereas a Mediterranean-style diet can protect against the disease. Antioxidants in the form of vitamins A, C, and E; physical activity; good sleep quality; smoking cessation; moderate alcohol consumption; and avoiding noise exposure are also beneficial. Conclusions: Adequate diet or nutritional interventions with lifestyle modification may protect against developing audio-vestibular dysfunction in elderly individuals.

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Can Nutritional Intervention for Obesity and Comorbidities Slow Down Age-Related Hearing Impairment?

Cited by 13 publications

References 81 publications

Hearing Loss due to Noise Exposure and its Relationship with Hypertension in Peruvian Workers

Hearing Loss due to Noise Exposure and its Relationship with Hypertension in Peruvian Workers

Understanding the role of inflammation in sensorineural hearing loss: Current goals and future prospects

Effects of Diet and Lifestyle on Audio-Vestibular Dysfunction in the Elderly: A Literature Review

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