Can Sexual Intercourse Be an Alternative Therapy for Distal Ureteral Stones? A Prospective, Randomized, Controlled Study

Re: Abdel-Kader MS. Evaluation of the efficacy of sexual intercourse in expulsion of distal ureteric stones. Int Urol Nephrol 2016 [Epub ahead of print]

“…The authors recommended that practicing sexual intercourse for 3-4 times/week for married male patients with distal ureteric stone (5-10 mm) increases the expulsion rate and decreases the frequency of renal colic and the needs for analgesic. These results are consistent with previous study by Doluoglu et al [2]. Doluoglu et al assumed sexual intercourse facilitates the ureteric stone expulsion associated with nitric oxide-mediated pathway.…”

Alpha blockers in the management of ureteric lithiasis: A meta-analysis

“…Results of quality assessment using the Cochrane Risk of Bias tool can be found in Figure 7. Overall, a high degree of bias was seen with only nine studies judged to be at low risk while 41 were judged to be intermediate risk and 17 high risk . The most common cause for bias was blinding of both participants and personnel and outcomes assessment.…”

The fragility of statistically significant findings from randomised controlled trials in the urological literature

“…Table lists the included RCTs, the year and journal of publication, the outcome considered, as well as the reported sample size, P value, and calculated Fragility Index. The median sample size (interquartile range [IQR]) was 99 (65, 179), whilst the median (IQR) event rate per study outcome was 38 (24, 65).…”