Can simultaneous contact allergies to phenyl glycidyl ether and epoxy resins of the bisphenol A/F‐types be explained by contamination of the epoxy resins?

Abstract

Most probably, the presence of PGE as a contaminant in epoxy resins is of minor importance for the sensitization, but possibly the contamination of PGE might elicit contact dermatitis in individuals with a high reactivity to PGE.

Contact allergy to reactive diluents and related aliphatic epoxy resins

“…At present, there are no products containing PGE in the Finnish Product Register of Chemicals. PGE is a known contaminant in commercial epoxy resins: in a Swedish study, concentrations in 20 products varied between 0.04% and 0.18% . The results of our chemical analyses were within the same range.…”

Sensitizing capacity and cross‐reactivity of phenyl glycidyl ether studied in the guinea‐pig maximization test

“…Exposure‐related simultaneous contact allergies to PGE and epoxy resins can be explained by PGE being present as part of ERSs, but contamination by PGE in epoxy resins could also be suspected. However, chemical analyses of a selection of commercial epoxy resins containing DGEBA and/or DGEBF have shown that sensitization from the comparatively low content of PGE is less likely to occur (13).…”

“…That could especially be the case for epoxy resins based on phenolic novolac because they have a smaller repetitive unit, consisting of one aromatic ring, than epoxy resins based on bisphenol A or F (11). However, chemical analyses of epoxy resins performed by us have shown that contamination of PGE in DGEBA‐R and epoxy resins of the bisphenol F‐type is a less likely explanation of simultaneous contact allergies to this reactive diluent and these resins (13).…”

Contact allergy to epoxy (meth)acrylates

“…Her elicitation threshold for bis-GA was also low, 10 ppm. In a recent series from Sweden, there was also a patient who reacted to 10 ppm DGEBA (35). In addition to the impurities of the test substance, impurities in the commercial bis-GMA products have presented another problem.…”