Patients who have immobilization and bedrest prone to have poor blood circulation to the area that contact the bed. This condition is triggering pressure ulcer that may impact on patients’ recovery process, burden, and conformity. In 4.0 industry, information, and communication technology (ICT) has implemented in many healthcare activities, including in the prevention of pressure ulcer. ICT provides a solution to prevent this unwanted condition in bedrest patients through many forms, but has not been mapped yet, especially for nursing. The purpose of this study is mainly to synthesize previous findings related to the adoption of ICT in pressure ulcer preventions. This study is a literature review which using several databases, namely Pubmed, Google Scholar, JMIR, IEEE, and Sage Journals. We used the PRISMA framework as a guideline to select the eligible articles that must be included to our study. We implemented Mixed Method Appraisal Tool to ensure the quality of articles in this review. Then, the data is synthesized and visualized in tabular. We gathered 2,081 articles from literature searching and obtained 12 eligible articles to be synthesized. Our Findings revealed that ICT adoption in ulcer pressure prevention was further than expected which the implementation of artificial intelligence (AI) was dominated in our findings. We also found that several technologies, such internet of things (IoT), were also implemented to send the patient’s data related to pressure ulcer periodically and provided the information for healthcare provider to formulate preventive interventions. Detection of pressure ulcer among patients may be done precisely by tomography technique in one study. Various ICT implementations in pressure ulcer prevention were promising to be adopted by healthcare providers, including nurses.