This article reviews strategies for radiation dose optimization for computed tomography (CT). A brief overview of dose metrics including computed tomographic dose index, dose length product and effective dose is provided. The impact of age and gender on the sensitivity to radiation is discussed with the aim of tailoring CT acquisition parameters to patient demographics. Dose reduction technologies are reviewed including: tube current modulation, kVp modulation, scan length modification, dynamic z-axis collimation, iterative reconstruction and dual energy. Optimal selection of CT acquisition parameters requires review of clinical information and patient demographics prior to imaging. The authors conclude that with the appropriate application of dose reduction technologies there can be substantial reduction in patient radiation dose while maintaining high diagnostic quality images.