Cancellous bone marrow grafts in irradiated dog and monkey mandibles

Marciant, Robert D.; Gonty, Arthur A.; Synhorst, John B.; Page, Lawrence R.

doi:10.1016/0030-4220(79)90095-1

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Particulate Bone Augmentation With Membranes1

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2015

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Cited by 16 publications

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“…[88][89][90][91] Burchardt 88 demonstrated that whereas cancellous grafts tend to repair completely with time, cortical grafts remain a mixture of necrotic and viable bone. Cancellous and particulate marrow grafts have shown more rapid vascularization and more osteogenic activity compared with autogenous block grafts.…”

Section: Particulate Bone Augmentation With Membranesmentioning

confidence: 99%

Surgery of the posterior mandible

Block

2015

Color Atlas of Dental Implant Surgery

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Section: Particulate Bone Augmentation With Membranesmentioning

confidence: 99%

Surgery of the posterior mandible

Block

2015

Color Atlas of Dental Implant Surgery

View full text Add to dashboard Cite

Distraction Osteogenesis

and¹,

Haggerty²

2015

Implant Site Development

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Partial characterization of rat marrow stromal cells

et al. 1991

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Fibroblast-like rat marrow stromal cell (CFU-F) cultures have been characterized in terms of their responsiveness to calciotropic hormones, metal ions, the nonsteroidal antiinflammatory drug, and by their putative paracrine role in the maintenance of active populations of osteoblasts at the marrow-bone interface. These studies indicate that CFU-Fs lack a complete osteoblast signature. Subconfluent CFU-Fs grown in the presence or absence of 10(-7) M dexamethasone lack receptors for PTH and calcitonin, and fail to show enhanced cAMP or cGMP responses to 10(-7) M 1-34 PTH (rat), or any evidence of osteocalcin production [+/- 10(-9) M 1,25-(OH)2D3]. Low concentrations of fluoride [10(-12) and 10(-9) M] stimulated CFU-F grown in vitro in serum-free media, though higher levels (10(-7) and 10(-6) M), inhibited growth in vivo and in vitro. Aluminum (10(-12)-10(-7) M) and ibuprofen (10(-7) M) did not alter normal growth patterns, indicating an action on bone cells more differentiated than CFU-Fs. Serum-free conditioned medium (CM) from control and ovariectomized (OVX)/OVX+ dihydrotachysterol-Rx rat CFU-F cultures was mitogenic for neonatal rat calvarial osteoblasts in vitro, but not for ROS 17/2.8 cells. The studies affirm the mesenchymal-like character of CFU-Fs and project their significant role in sustaining functional endosteal osteogenic cell populations.

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Cancellous bone marrow grafts in irradiated dog and monkey mandibles

Cited by 16 publications

References 4 publications

Surgery of the posterior mandible

Surgery of the posterior mandible

Distraction Osteogenesis

Partial characterization of rat marrow stromal cells

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