Cancer arising in a choledochal cyst in a 12-year-old girl

Iwai, Naoharu; Deguchi, Eiichi; Yanagihara, Jun; Iwai, Masaki; Matsuo, H.; Todo, Shinjiro; Imashuku, Shinsaku

doi:10.1016/0022-3468(90)90525-e

Cited by 66 publications

(41 citation statements)

References 7 publications

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“…The average age of patients of biliary tract cancer with PBM is 10 years younger than that of cancer without PBM [5], and very young teenagers having carcinoma with PBM [22,23] were reported, which were not seen in cancer patients without PBM.…”

Section: Biliary Tract Carcinomamentioning

confidence: 94%

Pancreaticobiliary maljunction and carcinogenesis to biliary and pancreatic malignancy

Funabiki

Matsubara²,

Miyakawa

et al. 2008

Langenbecks Arch Surg

160

146

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Section: Biliary Tract Carcinomamentioning

confidence: 94%

Pancreaticobiliary maljunction and carcinogenesis to biliary and pancreatic malignancy

Funabiki

Matsubara²,

Miyakawa

et al. 2008

Langenbecks Arch Surg

160

146

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“…Dysplasia and overt malignancy are age-related features with the youngest patient so far reported a 12-year-old girl with a large cystic malformation who, at presentation, had an invasive, inoperable adenocarcinoma of the distal duct. 33 A number of different histological types have been reported; most are adenocarcinomas of the bile ducts or gallbladder, although squamous carcinoma (presumably arising in an area of squamous metaplasia) is also possible. Rarities included carcinoma arising in a villous adenoma 34 and cancer of the distal duct within the pancreas.…”

Section: Risk Of Malignancy In Choledochal Malformationmentioning

confidence: 99%

Congenital Choledochal Malformation: Not Just a Problem for Children

Dabbas

Davenport

2009

annals

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Choledochal cysts remain relatively uncommon in Western Europe and the US, although they are appreciably more common in Asia. Their aetiology remains obscure although abnormalities of the pancreaticobiliary junction may be the primary pathology in some, with biliary dilatation following reflux of activated pancreatic secretions. Most anomalies will present in childhood with obstructive jaundice or abdominal pain; a proportion may only present for the first time during adulthood, and some of these will show malignant transformation. The classical triad of pain, jaundice and a palpable mass is, however, not common. Complete cyst excision, where possible, and biliary reconstruction remain the aims for most types although there is still some controversy about the type of reconstruction. Laparoscopic reconstruction is possible but is still very much an advanced technique. The risk of long-term problems post-surgery is significant. Whether this is due to recurrent pancreatitis secondary to the retained common channel and/or a distal stump, or due to the development of biliary tract malignancy is still a cause for concern and indicates the need for adequate, prolonged follow-up.

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“…Acute pancreatitis often reveals the choledochal cyst. Other revealing complications are lithiasis, which can block the common bile duct, cholangitis, Gallbladder perforation with choleperitoneum, biliary cirrhosis, and secondary degeneration of the cystic wall which has been reported from the age of 12 years [4]. In 1723, Vater described for the first time the dilatations of the biliary tree.…”

Section: Discussionmentioning

confidence: 99%

Cystic Enlargement of the Bile Duct: Case Report and Review of Literature

Ovungu¹,

Mvumbi²,

Ossibi³

et al. 2017

OJRad

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Congenital cystic dilatations of the bile duct are rare malformations representing 1 per 13,000 births with a female predominance. Diagnosis of this pathology is based on radiological imaging especially radiological investigations conducted on an ultrasound coupled with Computed tomography (CT) scan and especially a bili-MRI which allows the analysis of the bile duct malformations and the anomalies of the pancreaticobiliary junction. We will discuss in this clinical case the various radiological aspects of cystic dilatations of the biliary duct.

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Cancer arising in a choledochal cyst in a 12-year-old girl

Cited by 66 publications

References 7 publications

Pancreaticobiliary maljunction and carcinogenesis to biliary and pancreatic malignancy

Pancreaticobiliary maljunction and carcinogenesis to biliary and pancreatic malignancy

Congenital Choledochal Malformation: Not Just a Problem for Children

Cystic Enlargement of the Bile Duct: Case Report and Review of Literature

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