Cancer Cells in Prostatic Secretions

Fine Needle Aspiration Biopsy of the Prostate

“…Also, the possibility of contamination from other parts of the urinary tract cannot be discounted. It is of no value in latent or occult carcinoma (6,13,22), though some authors have been highly successful in the diagnosis of prostatic carcinoma by this method (16). Popular concensus of opinion agrees that 85-950/o of prostatic carcinomas arise in the periphery of the gland, either capsular or subcapsular.…”

Carcinoma of the Prostate

“…(c) Prosfatic Smears. -Herbut and Lubin (1947) reported on the diagnosis of carcinonia by the presence of malignant cells i n the prostatic secretions. using the Papanicolaou technique.…”

“…This method has been enthusiastically followed in America and very good results have been published with five-year cure rates of up to 50 per cent. or more for selected cases (Hinman, 1948;Kimbrough, 1956). This operation has not been viewed with favour in Great Britain because one sees so few patients in whom it can be contemplated.…”

Summary of Currently Employed Prostatic Biopsy Methods, With Comments Concerning Combined Transrectal Biopsy and Radical Retropubic Prostatectomy

“…5. Prostatic Smear.-Of those investigators who have reported on the use of prostatic smear as a means of diagnosing carcinoma of the prostate, only an occasional one suggests that it is a procedure of merit, Herbut and Lubin (1947) studied the prostatic secretion from 100 patients and found carcinoma in seventeen. The diagnosis was confirmed in ten and was " reasonably certain " but unconfirmed in an additional six.…”