Cancer de la prostate localisé à haut risque de récidive: résultats de la prise charge

Babacar, S.; Aissatou, B.N.; Cyrille, Z.O.; Thiam, Amath; Alioune, S.; Sow, Yaya; Fall, B.; Denis, Bertrand; Hamidou, Zineb; Thiapato, F.S.; Ndongo, Modou; Seck, Ndiogou; Diao, Bo; Ahmed, F.P.; Khassim, N.A.; M, Bâ

doi:10.1016/j.afju.2018.11.001

Cited by 2 publications

(6 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Two studies from the region have reported exclusively on the management of localized prostate cancer. A prospective study by Kyei et al [10] from Ghana assessed the management and outcome of 20 patients who underwent radical prostatectomy; and a retrospective study by Babacar et al [21] from Senegal reviewed management of men with high-risk localized prostate cancer. The study population of both publications combined is minimum, so conclusions drawn from these reports remain underpowered.…”

Section: Discussionmentioning

confidence: 99%

“…The true incidence of very-low-risk prostate cancer in the African population is unknown. Babacar et al from Senegal [21] reported T1 - T2a disease but their corresponding PSA levels, Gleason grade, percentage of positive core biopsy and PSA density were not available for prostate cancer risk stratification. However, most of the prostate cancers in the above study along with Yamoah et al [26] from Ghana were Gleason grade group 1 (Table 3 [10, 14-22, 24-26]).…”

Section: Discussionmentioning

confidence: 99%

“…Not many sub-Saharan publications report the management of localized prostate cancer specifically. However, two studies including one from Ghana and Senegal reviewed the outcome of radical prostatectomy in men with localized disease [10, 21].…”

Section: Discussionmentioning

confidence: 99%

“…A retrospective study in Senegal involving 35 men with high-risk organ-confined prostate cancer who underwent radical prostatectomy showed that incontinence and erectile dysfunction were the commonest postoperative complications [21]. Recurrence-free survival at 5 years was 70% and the overall survival at 6 years was 90%.…”

Section: Discussionmentioning

confidence: 99%

“…A pool analysis of the reviewed data (Table 2 [8, 10, 12-16, 18-23]) showed very elevated PSA levels with a range of 0 to 21,660 ng/mL and mean PSA of approximately 438.9 ng/mL. However, reports by Kyei et al [10] and Babacar et al [21] had a study population of localized prostate cancer exclusively and reported a much lower mean PSA at 16.12 ± 13.68 and 25 respectively. The predominant histological type in sub-Saharan nations is adenocarcinoma with a range of 95-100%.…”

Section: Literature Retrievedmentioning

confidence: 99%

See 4 more Smart Citations

A Review of Localized Prostate Cancer: An African Perspective

et al. 2019

View full text Add to dashboard Cite

Prostate cancer is the second most common malignancy in males and the sixth leading cause of cancer mortality in men with a relatively higher death rate in men of African descent. In the United States and other parts of Europe, more than 80% of diagnosed prostate cancer is localized, and 80-90% of these men receive some form of treatment. The projected data may not be a direct reflection of the disease in the sub-Saharan region as less than 40% presents with localized disease. Results from prostate cancer screening have shown that most African men in the sub-region have little knowledge of the disease. There are recommended international guidelines for the management of localized prostate cancer, however, a guideline in a local context could be ideal.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Literature Retrievedmentioning

confidence: 99%

See 3 more Smart Citations

A Review of Localized Prostate Cancer: An African Perspective

et al. 2019

View full text Add to dashboard Cite

show abstract

Prostate Cancer in the Thies Region, Senegal: Epidemiological, Diagnostic and Therapeutic Aspects

Kouka,

Bentefouet,

Jalloh

et al. 2024

OJU

View full text Add to dashboard Cite

Introduction: Prostate cancer is the leading urological cancer. It is the most common cancer in men over 50. Objective: To determine the epidemiological, diagnostic and therapeutic characteristics of prostate cancer in hospitals in the Thiès region. Patients and Methods: We conducted a descriptive study from January 1 st , 2015 to December 31 st , 2020. We included all cases of primary prostate cancer confirmed on histology. Results: We collected data on 318 cases of primary prostate cancer during the study period. Mean patient age was 72.7 years (Range: 49; 94 years). Family history of prostate cancer was found in 22 patients (6.91%). The average consultation time was 18.6 months. The circumstances of discovery were dominated by obstructive voiding disorders (97.16%). Digital Rectal examination was suggestive in 55.40% of patients. PSA level was above 20 ng/ml in 76.7% of patients. Prostatic adenocarcinoma was the only histological type (100%). Localized cancer represented 7.2% and locally advanced cancer occurred in 36.5% of cases, while metastatic cancer accounted for 56.3%. Radical prostatectomy was performed in 3.18% of cases. Mortality rate was estimated at 8.50% after 1 year. Conclusion: Prostate cancer is the leading urological cancer in the Thies region. It is characterized by the predominance of locally advanced and metastatic forms.

show abstract

Cancer de la prostate localisé à haut risque de récidive: résultats de la prise charge

Cited by 2 publications

References 23 publications

A Review of Localized Prostate Cancer: An African Perspective

A Review of Localized Prostate Cancer: An African Perspective

Prostate Cancer in the Thies Region, Senegal: Epidemiological, Diagnostic and Therapeutic Aspects

Contact Info

Product

Resources

About