Cancer in pregnancy: breast cancer

Breast cancer associated with pregnancy – a review of therapeutic approaches

“…Clinical manifestations and diagnosis. PABC manifests as a painless lump accompanied by discharge and retraction of the nipples, as well as redness and ulceration of the skin [20]. Tumour size determines the determination of tumour stage and the selection of an appropriate treatment plan.…”

“…Diagnostic mammography is safely performed in pregnant women and, due to its low radiation of 200 -400 mrad, does not significantly affect foetal development [24]. Nowadays, a new method of breast imaging is contrast-enhanced mammography (CEM), which involves the use of iodine contrast, but its use is contraindicated in pregnant women due to the penetration of the substance through the placenta and into the foetus [20]. Based on studies, the sensitivity of ultrasound in detecting breast cancer in pregnant patients is 95.7%, while that of mammography is 56.5% [25].…”

First Reported Case of Successful Conception and Delivery During Stage IV Breast Cancer Treatment: A Case Report and Literature Review

“…The incidence of pregnancy-associated BC has been observed to rise, mirroring the trend of delayed pregnancies in women. Pregnancy-associated BC is seen in 3 out of 1,000 pregnancies [1]. This particular BC subtype exhibits a heightened degree of aggressiveness, frequently compounded by diagnostic delays attributable to physiological alterations occurring during pregnancy and a discernible lack of awareness within the medical community.…”