Cancer incidence among workers in the asbestos-cement producing industry in Norway

Ulvestad, Bente; Kjærheim, Kristina; Martinsen, Jan Ivar; Damberg, Grete; Wannag, Axel; Mowé, G; Andersen, Aage

doi:10.5271/sjweh.693

Cited by 47 publications

(32 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…But still these concentrations were low compared with the airborne dust levels reported in other studies. In a recent paper from Norway the gravimetric data shoved concentrations of 0.2-22.8 mg/m 3 , and the fiber concentrations were estimated to be between 100 and 1900 f/ml in 1964, with less than 5 f/ml for later years (20). In the Norwegian study no case of mesothelioma was found among those with less than 5 years of employment.…”

Section: Discussionmentioning

confidence: 89%

“…The smoking habits of the cohort members were not known. The Norwegian study (20) showed an excess risk of lung cancer, but no trend in risk by duration of employment. This lack of dose-response relationship is in accordance with the results of other Nordic studies from the asbestos-cement industry with duration of exposure as a dose surrogate (20,23).…”

Section: Discussionmentioning

confidence: 92%

See 1 more Smart Citation

Cancer mortality and morbidity among Lithuanian asbestos-cement producing workers

Smailytė¹,

Kurtinaitis²,

Andersen³

2004

Scand J Work Environ Health

Self Cite

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 89%

Section: Discussionmentioning

confidence: 92%

Cancer mortality and morbidity among Lithuanian asbestos-cement producing workers

Smailytė¹,

Kurtinaitis²,

Andersen³

2004

Scand J Work Environ Health

Self Cite

View full text Add to dashboard Cite

“…Relative risks of mesothelioma following asbestos exposure have varied widely in previous studies. Two recent cohort studies in Norway and Israel found standardized incidence ratios above 5000 (Tulchinsky et al, 1999;Ulvestad et al, 2002). The risk of developing mesothelioma has been estimated as proportional to a third or fourth power of time since first occupational exposure to asbestos (Peto et al, 1982).…”

Section: Discussionmentioning

confidence: 99%

“…Cohort studies found increased incidence and mortality from mesothelioma among (chiefly male) asbestos workers employed in mining (Piolatto et al, 1990;McDonald et al, 1993), but mainly textile and manufacture (Newhouse and Berry, 1979;Berry et al, 2000;Yano et al, 2001), insulation (Selikoff et al, 1979) and asbestos-cement factories (Tulchinsky et al, 1999;Ulvestad et al, 2002). Mesothelioma risk varied widely among different studies, according to types of asbestos involved (chrysotile, amosite or crocidolite) (Hodgson and Darnton, 2000) and levels of exposure (Doll and Peto, 1985).…”

mentioning

confidence: 99%

Cancer mortality in a cohort of asbestos textile workers

et al. 2005

View full text Add to dashboard Cite

A cohort of 889 men and 1077 women employed for at least 1 month between 1946 and 1984 by a former Italian leading asbestos (mainly textile) company, characterised by extremely heavy exposures often for short durations, was followed up to 1996, for a total of 53 024 person-years of observation. Employment data were obtained from factory personnel records, while vital status and causes of death were ascertained through municipality registers and local health units. We observed 222 cancer deaths compared with 116.4 expected (standardized mortality ratio, SMR ¼ 191). The highest ratios were found for pleural (SMR ¼ 4105), peritoneal (SMR ¼ 1817) and lung (SMR ¼ 282) cancers. We observed direct relationships with duration of employment for lung and peritoneal cancer, and with time since first employment for lung cancer and mesothelioma. Pleural cancer risk was independent from duration (SMR ¼ 3428 for employment o1 year, 7659 for 1 -4 years, 2979 for 5 -9 years and 2130 for X10 years). Corresponding SMRs for lung cancer were 139, 251, 233 and 531. Nonsignificantly increased ratios were found for ovarian (SMR ¼ 261), laryngeal (SMR ¼ 238) and oro-pharyngeal (SMR ¼ 226) cancers. This study confirms and further quantifies the central role of latency in pleural mesothelioma and of cumulative exposure in lung cancer.

show abstract

“…Some recent studies clearly show the influence of exposure duration on mesothelioma risk. Ulvestad et al 58) have analyzed the cancer incidence among workers of an asbestoscement industry in Norway. No mesothelioma case was observed among people with less than 5 yr of employment.…”

Section: Duration Of Exposurementioning

confidence: 99%

Malignant Mesothelioma: Global Incidence and Relationship with Asbestos

2007

View full text Add to dashboard Cite

Mesothelioma incidence varies markedly from one country to another. The highest annual crude incidence rates (about 30 cases per million) are observed in Australia, Belgium, and Great Britain. A lot of data indicate a relationship between mesothelioma and asbestos. The hot areas for mesothelioma exactly correspond to the sites of industries with high asbestos use, such as shipbuilding and asbestos-cement industry. However, in many countries with high asbestos consumption, mesothelioma incidence is low. The reasons for this fact are not clear. The latency periods elapsing between first exposure to asbestos and development of mesothelioma are mostly longer than 40 yr. An inverse relationship exists between intensity of asbestos exposure and length of the latency period. Mesothelioma generally develops after long-time exposures to asbestos. Some recent studies show that the risk increases with the duration of exposure. Possible co-factors in the pathogenesis of asbestos-related mesothelioma include genetic predisposition, diets poor in fruit and vegetables, viruses, immune impairment, recurrent serosal inflammation. The study of co-morbidity in mesothelioma could give an insight into the pathogenesis of the tumor. While a levelling-off in mesothelioma incidence has been registered in some countries, a worsening of the epidemic is predictable in large parts of the world.

show abstract

Cancer incidence among workers in the asbestos-cement producing industry in Norway

Cited by 47 publications

References 31 publications

Cancer mortality and morbidity among Lithuanian asbestos-cement producing workers

Cancer mortality and morbidity among Lithuanian asbestos-cement producing workers

Cancer mortality in a cohort of asbestos textile workers

Malignant Mesothelioma: Global Incidence and Relationship with Asbestos

Contact Info

Product

Resources

About