Cancer Incidence in Egypt: Results of the National Population-Based Cancer Registry Program

Abstract

Background. This paper aims to present cancer incidence rates at national and regional level of Egypt, based upon results of National Cancer Registry Program (NCRP). Methods. NCRP stratified Egypt into 3 geographical strata: lower, middle, and upper. One governorate represented each region. Abstractors collected data from medical records of cancer centers, national tertiary care institutions, Health Insurance Organization, Government-Subsidized Treatment Program, and death records. Data entry was online. Incidence rates were calculated at a regional and a national level. Future projection up to 2050 was also calculated. Results. Age-standardized incidence rates per 100,000 were 166.6 (both sexes), 175.9 (males), and 157.0 (females). Commonest sites were liver (23.8%), breast (15.4%), and bladder (6.9%) (both sexes): liver (33.6%) and bladder (10.7%) among men, and breast (32.0%) and liver (13.5%) among women. By 2050, a 3-fold increase in incident cancer relative to 2013 was estimated. Conclusion. These data are the only available cancer rates at national and regional levels of Egypt. The pattern of cancer indicated the increased burden of liver cancer. Breast cancer occupied the second rank. Study of rates of individual sites of cancer might help in giving clues for preventive programs.

Association of serum levels of epidermal growth factor with disease severity in patients with unresectable hepatocellular carcinoma

“…[1,2] In Egypt, incidences of liver cancer have risen dramatically over the last two decades, and now it is the most common cancer in men and the second most common cancer in women, [3] with an annual rate of HCC development of 1-4%, when hepatitis C virus (HCV)-related cirrhosis is established. [1] Patients suffering from HCC unlike most solid tumors are confronted with the coexistence of two life-threatening conditions, malignancy and cirrhosis, which makes their prognostic assessments difficult.…”

Effect of intervention educational program about breast cancer preventive measures on Assuit University employees’ knowledge, practices & health habits

“…As mentioned in a study done in Egypt by Ibrahim et al, (4) who found that Upper Egypt represents the most prevalent incidence compared to lower & middle Egypt (38.7%, 33.2 % & 26.8 % respectively)these findings alarm the health care providers especially in Upper Egypt to increase women awareness toward breast cancer preventive measures through implementing an intervention educational program.…”

“…(1) According to World Health Organization 2010, there were about 519,000 women who die from breast cancer annually and about one million of women develop breast cancer each year. (2,3) The most recent study by Ibrahim et al (4) reported that cancer incidence rates based on national and regional level of Egypt revealed 157 per 100,000 among females. The commonest site was breast (32.0%) and the study added that by 2050, this incidence will be a 3-fold increase cancer relative to 2013 estimated rates.…”

Synthesis and Antiproliferative Activity of Novel Neocryptolepine-Hydrazides Hybrids

“…As part of our ongoing program for developing anticancer agents based on a natural product scaffolds herein, we synthetized novel analogues of neocryptolepine compounds bearing sulfonyl-and carbonyl hydrazide moieties and evaluated their anticancer activity against the most common cancer in Egypt hepatocellular carcinoma (Ibrahim et al, 2014). …”