Cancer mortality of granite workers.

Koskela, Riitta‐Sisko; Klockars, Matti; Järvinen, Erkki; Kolari, P J; Rossi, A

doi:10.5271/sjweh.2088

Cited by 35 publications

(17 citation statements)

References 18 publications

(24 reference statements)

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“…Inconsistencies in the earlier reported results can be explained by differences in (i) study design, (ii) the internal structure of the cohort [period of entry, period of follow-up, age structure, and occurrence of disease (eg, tumors) in the population], (iii) potential confounders and methods of analysis , and (iv) differences in exposure intensity and duration (18,19).…”

Section: Discussionmentioning

confidence: 99%

“…The other tumors reported as primary (N = 9) or secondary (N = 2) causes were not concentrated in any specific category of cancer diagnosis. A closer analysis of the cancer mortality can be found in another paper (19).…”

Section: Mortalitymentioning

confidence: 93%

“…This conclusion is not contradictory to earlier proposed connections between lung cancer and silicosis. The association between silica exposure and cancer has been discussed in detail in a separate paper (19).…”

Section: Cancermentioning

confidence: 99%

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Mortality and disability among granite workers.

Koskela¹,

Klockars²,

Järvinen³

et al. 1987

Scand J Work Environ Health

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KOSKELA R-S, KLOCKARS M, JARVINEN E, KOLARI PJ, ROSSI A. Mortality and disability among granite workers. Scand J Work Environ Health I3 (1987) 18-25. The objecti ve of the present study was to investigate the mortality, disability, and long-term morbidity of granite workers. The study included 1 026 workers hired between 1940and 197I and followed until the end of 1981.The total number of deaths was 235, and the expected number was 229.7. Excess mortality rates were observed for respiratory diseases (observed/expected = 28/13 .9). The number of tumor death s was 46 (expected 44.9). Excess lung cancer mortality was evident at 15 to 35 years of latency; the observed number of lung cancer deaths for the follow-up period of 25 to 29 years was 8, while 2.1 were expected. Mortality from cardiovascular diseases and violent deaths was slighty less than expected. The results for disability and long-term morbidity showed elevated incidence and prevalence rates for respiratory diseases and rheumatoid arthritis . The observed number of disability pensions due to rheumatoid arthritis in 1981 was 10 observed versus 1.8 expected, and the observed number of patients granted free medication was 19 versus 8.1 expected. The results indicate that granite dust exposure per se may be an etiologic and pathogenetic factor for lung cancer, cancer of the gastrointestinal tract, and some extrapulmonary nonmalignant chronic diseases.

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Section: Discussionmentioning

confidence: 99%

Section: Mortalitymentioning

confidence: 93%

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Mortality and disability among granite workers.

Koskela¹,

Klockars²,

Järvinen³

et al. 1987

Scand J Work Environ Health

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“…Data from the 1973 cross sectional survey showed that smoking habits were comparable among workers at the two mines, with current smokers accounting for 64-7% in the mine A and 67 1% in the mine B workforce; corresponding figures for former smokers were 7 9 and 7-2%.24 National and regional data on smoking habits are available for the general male population aged >1134 or >14"3 not broken down by age groups, thus not directly comparable with the mining population surveyed in 1973. A survey on smoking habits among students in northern Sardinia found that current smokers accounted for 26% of males aged [11][12][13][14][15][16][17][18][19][20], and the same proportion was 63% at age 20.36 This figure is probably the closest to the general Sardinian male population of the same age as miners surveyed in 1973, but it is not sufficiently precise to estimate the confounding effect of smoking on risk of lung cancer in our cohort study. Other authors used the SMR for cancer sites other than the lung that are presumably related to smoking (oral cavity, pancreas, larynx, kidney, and bladder) to evaluate the confounding effect on the risk estimate for lung cancer.5 With the same approach, a total of 16 deaths from those cancers were observed among underground miners in mine A v 16-7 expected, and 21 were observed v 21-5 expected among underground miners in mine B.…”

Section: Discussionmentioning

confidence: 83%

Mortality of Sardinian lead and zinc miners: 1960-88.

Cocco¹,

Carta²,

Belli³

et al. 1994

Occup Environ Med

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The mortality of 4740 male workers of two lead and zinc mines was followed up from 1960 for subjects employed 26 years, was, however, found among underground workers in mine A who on the average experienced an exposure to radon daughters 10-fold higher than those of mine B. By contrast, despite their higher exposure to silica, mine B underground workers experienced a lower than expected lung cancer mortality. A ninefold increase in risk of peritoneal and retroperitoneal cancer combined was also found among underground workers ofmine A (SMR 917; 95% CI 250-2347; based on four deaths). A causal association with workplace exposures is unlikely, however, as the SMR showed an inverse trend by duration of employment. These findings are consistent with low level exposure to radon daughters as a risk factor for lung cancer among metal miners. Exposure to silica at the levels estimated for the mine B underground environment did not increase the risk of lung cancer. (Occup Environ Med 1994;51:674-682)

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“…A Finnish study (24) among granite workers showed an overall standardized mortality ratio (SMR) of 129 for lung cancer (22 observed, 17. I expected).…”

Section: Discussionmentioning

confidence: 99%