Cancer of the Uterine Cervix: An Enquiry Into Predisposing Factors, With Special Reference to Earlier Diagnosis

Lawson, Millie

doi:10.1111/j.1471-0528.1957.tb06277.x

Cited by 18 publications

(2 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Similar findings have been reported by other workers. [13][14][15][16][17][18][19][20][21] Comparatively low incidence of cancer of the cervix in MusIim women has been recorded in all parts of India, with few exceptions. Apparently high incidence recorded in the latter was probably due to a relatively high Muslim population in those cities.…”

Section: Discussionmentioning

confidence: 99%

Factors influencing cancer of the uterine cervix in north India

Wahi

Mali

Luthra

1969

Cancer

View full text Add to dashboard Cite

Cancer of the uterine cervix is the most common malignant tumor among women in India. T h e varying frequency of cervix carcinoma in different parts of the country is dependent upon certain environmental factors, such as socioeconomic conditions, sexual experience, age a t marriage, fertility, and penile hygiene. This paper is based upon a clinical and statistical analysis of 693 cases of cervix carcinoma diagnosed from a population study of 39,587 women who were screened by vaginal smear examination. T h e findings of this study suggest the importance of the socioeconomic factors of poverty, rapid sexual maturation, early marriage and consequent early sexual experience, and early p r e g nancy and multiparity in producing the high incidence of cancer of uterine cervix in Indian women. ARCINOMA OF THE UTERINE CERVIX IS THE C most common malignant tumor among I224 CANCER May 1969 Vol. 23

show abstract

Section: Discussionmentioning

confidence: 99%

Factors influencing cancer of the uterine cervix in north India

Wahi

Mali

Luthra

1969

Cancer

View full text Add to dashboard Cite

show abstract

“…11 In our study, the cases have all reported of having only one sexual partner throughout their reproductive period, although most of them have had a prolonged married life. The prolonged sexual exposure resulting in cervical cancer has been reported by Lawson et al 17 to be due to the effect of the excess mucus secreted by the mucus-bearing cells that gets dissolved by alkalis in the cervical mucosa, and then precipitated by acids from the vaginal mucosa. 18 This is reported to result in removal of the surface mucosa, thus causing cervical trauma leading to the proliferative and hyperplastic changes.…”

Section: Jsafomsmentioning

confidence: 97%

Changing Trends in the Epidemiology of Cervical Cancer in Upper Middle Class Women

Srinivasan¹,

Meenakshi²,

Mouleeswaran³

et al. 2018

Journal of SAFOMS

View full text Add to dashboard Cite

Introduction: Changing trends in the epidemiology of cervical cancer are reported from developing countries, but the new factors are not well documented, especially socioeconomic (SE) status. Aim:To study the prevalence and factors associated with cervical cancer in upper middle SE class women from a tertiary care hospital in Chennai, South India. Materials and methods:This is a case-control study of cases with cervical cancer and twice the number of asymptomatic controls, among women who underwent papanicolaou (PAP) smear test during 2009 to 2015.Results: Of the 3,536 PAP smears examined, 48 (1.36%) had cervical cancer and 96 age-and year-matched controls were selected for the cases. The mean (± standard deviation, SD) age of cases was 51.3 (± 12.7) years and controls was 51.7 (± 12.7) years (p not significant, NS). Over 90% of both groups underwent surgical sterilization and had long married lives. The median parity of cases and controls was 2. Parity was 3 or more in 22 (44.9%), compared with 27 (28.1%) in controls (p < 0.05; relative risk, RR: 1.6 and 95% confidence interval, CI: 1.3-1.9). Among all the cases, 23 (48.0%) were asymptomatic. More than half, 28 (58.3%), of the cases and 50 (52.1%) of the controls had attained menopause (p = NS). About 7 (25%) of these cases reported postmenopausal bleeding (PNB). Conclusion:Among the PAP smears tested, high prevalence (1.36%) of cervical cancer was noted. The associated factors were age >50 years, median parity of 2, history of PNB, and a long duration of sexual exposure. Nearly half the cases were asymptomatic, highlighting the need for routine screening of all postmenopausal women.

show abstract

Epidemiologic studies on uterine cancer at Cancer Institute Hospital, Tokyo, Japan

Masubuchi¹,

Nemoto²

1972

Cancer

View full text Add to dashboard Cite

Five hundred and seventy‐two patients with uterine carcinoma, treated at the Department of Gynecology, Cancer Institute Hospital, Tokyo, were interviewed, and 200 healthy women were also interviewed as controls. The results are as follows: 1. the age at first intercourse is lower in the carcinoma group; 2. the carcinoma group showed increasing parity; 3. all the unmarried patients in the cervical carcinoma group have had sexual intercourse; 4. patients having had syphilis were more numerous in the uterine carcinoma group, and the Wasser‐mann‐positive patients were also significantly higher in this group; 5. the proportion of patients whose husbands had phimosis was higher in the cervical carcinoma group, and 6. the proportion of patients with uterine carcinoma who had mothers with uterine carcinoma was higher than the control group. It is concluded that uterine carcinoma has some genetic background and that early age at first intercourse and other cervical tissue contaminant factors are important.

show abstract

Cancer of the Uterine Cervix: An Enquiry Into Predisposing Factors, With Special Reference to Earlier Diagnosis

Cited by 18 publications

References 18 publications

Factors influencing cancer of the uterine cervix in north India

Factors influencing cancer of the uterine cervix in north India

Changing Trends in the Epidemiology of Cervical Cancer in Upper Middle Class Women

Epidemiologic studies on uterine cancer at Cancer Institute Hospital, Tokyo, Japan

Contact Info

Product

Resources

About