Cancer preventive effect of Thai rat-tailed radish (Raphanus sativus L. var. caudatus Alef)

The primary active components, antioxidant properties, and differential metabolite profiles of radish sprouts (Raphanus sativus L.) upon domestic storage: analysis of nutritional quality

“…As important secondary metabolites in plants, phenolic compounds, such as phenolic acids, flavonoids, anthocyanins, and procyanidines, have numerous biological effects: they are known to reduce the risk of cancer, heart disease, and diabetes, inhibition of plasma platelet aggregation, cyclooxygenase (COX) activity, and histamine release, in vitro antibacterial, antiviral, anti‐inflammatory, and anti‐allergenic effects . Isothiocyanates are degradation products of glucosinolates, especially sulforaphane, and they have good antioxidant, anti‐cancer, and cancer‐preventive effects . The nutritional value of Cruciferae sprouts is much higher than that of the mature vegetables; Cevallos reported that the phenolic content of broccoli, cabbage, radish, and other cruciferous sprouts is approximately ten times that of mature vegetables.…”

“…[4][5][6] Isothiocyanates are degradation products of glucosinolates, especially sulforaphane, and they have good antioxidant, anti-cancer, and cancer-preventive effects. 7,8 The nutritional value of Cruciferae sprouts is much higher than that of the mature vegetables; Cevallos 3 reported that the phenolic content of broccoli, cabbage, radish, and other cruciferous sprouts is approximately ten times that of mature vegetables.…”

Sulforaphene inhibits triple negative breast cancer through activating tumor suppressor Egr1

“…Accumulated epidemiologic studies reported that 67 % of 87 case-control studies found an inverse association between some type of cruciferous vegetable intake and cancer risk [8]. Sulforaphene (SFE, 4-methylsufinyl-3-butenyl isothiocyanate), a member of isothiocyanate family derived from radish [9], has shown a great potential as an anticancer agent [10][11][12]. Several recent case-control studies in the US, Sweden, and China found that measures of cruciferous vegetable intake were significantly lower in women diagnosed with breast cancer than in cancer-free control groups [13][14][15].…”

Developing Stable Cultivar through Microspore Mutagenesis in ×<i>Brassicoraphanus koranhort</i>, Inter-Generic Allopolyploid between <i>Brassica rapa</i> and <i>Raphanus sativus</i>

“…These rates might be criteria for determining the stability of allopolyploids, although the true threshold has not been es- Sulforaphene, a hydrolytic product of glucoraphenin, is a major isothiocya- nate in baemoochae seeds [9]. Many studies have reported biological effects of sulforaphene, including antimicrobial, antifungal, antibacterial, nematocidal, and allelopatic properties [28]- [33]. The total glucosinolate content of BB#5 was slightly lower than that of BB#1, while the glucoraphenin content of the two lines was similar.…”