2012
DOI: 10.1186/1476-069x-11-s1-s9
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Cancer risk and the complexity of the interactions between environmental and host factors: HENVINET interactive diagrams as simple tools for exploring and understanding the scientific evidence

Abstract: BackgroundDevelopment of graphical/visual presentations of cancer etiology caused by environmental stressors is a process that requires combining the complex biological interactions between xenobiotics in living and occupational environment with genes (gene-environment interaction) and genomic and non-genomic based disease specific mechanisms in living organisms. Traditionally, presentation of causal relationships includes the statistical association between exposure to one xenobiotic and the disease corrected… Show more

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Cited by 12 publications
(12 citation statements)
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“…Previous study done by (12) , observed increased cancer rates among females nearly everywhere in Europe. These finding might be due to increased rate of cancer breast which is the most frequently occurring cancer in females.…”
Section: In Order To Adopt Effective Preventive Measures and The Assomentioning
confidence: 88%
“…Previous study done by (12) , observed increased cancer rates among females nearly everywhere in Europe. These finding might be due to increased rate of cancer breast which is the most frequently occurring cancer in females.…”
Section: In Order To Adopt Effective Preventive Measures and The Assomentioning
confidence: 88%
“…The combination of these two steps to produce the azide in situ not only provided a one-pot, single step reaction to produce the bis-flavone dimers but also avoids the production of the highly reactive primary azide. In order to be classified as a click chemistry reaction the reaction must adhere to certain rules, such as being wide in scope, provide high yields, water and oxygen insensitivity and easy to perform with readily available reagents [25]. The formation of these dimers was performed following the click chemistry guidelines as the reaction took place in a very mild environment using a solvent system of a 1:1 ratio of water and tertiary butanol.…”
Section: Chemistrymentioning
confidence: 99%
“…The true relationships between the development of cancer and concurrent exposures to a wide variety of chemical and natural carcinogens in conjunction with the influences of lifestyle factors throughout an individual’s lifetime are not (and may never be) well understood [6,18,19]. …”
Section: Introductionmentioning
confidence: 99%