Cancer Risk in Patients With Chronic Urticaria

Chen, Yi Ju; Wu, Chun Ying; Shen, Jui-Lung; Chen, Tzu Ting; Chang, Yun Ting

doi:10.1001/archdermatol.2011.682

Cited by 60 publications

(48 citation statements)

References 28 publications

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“…According to Barcelos et al [22], the caffeine concentration in the husks of Arabica coffee varies between 0.5% and 1.3%, thus supporting the amount of caffeine found in the coffee husks used in this experiment. Caffeine was the substance responsible for the clinical signs observed, given that the mycotoxin analysis and the absence of insecticides in coffee husks excluded other conditions due to intoxication that exhibit neurological signs in horses, such as leukoencephalomalacia [23], and those that include signs of hyperexcitability, such as intoxication by chlorinated insecticides [24]. Furthermore, cattle have been shown to display signs of intoxication after one week of ingesting 3 kg, on average, of coffee husks used as bedding in their stalls [21].…”

Section: Discussionmentioning

confidence: 99%

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Equine poisoning by coffee husk (Coffea arabicaL.)

et al. 2012

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BackgroundIn Brazil, coffee (Coffea arabica) husks are reused in several ways due to their abundance, including as stall bedding. However, field veterinarians have reported that horses become intoxicated after ingesting the coffee husks that are used as bedding. The objective of this study was to evaluate whether coffee husk consumption causes intoxication in horses.ResultsSix horses fed coast cross hay ad libitum were given access to coffee husks and excitability, restlessness, involuntary muscle tremors, chewing movements and constant tremors of the lips and tongue, excessive sweating and increased respiration and heart rates were the most evident clinical signs. Caffeine levels were measured in the plasma and urine of these horses on two occasions: immediately before the coffee husks were made available to the animals (T0) and at the time of the clinical presentation of intoxication, 56 h after the animals started to consume the husks (T56). The concentrations of caffeine in the plasma (p < 0.001) and urine (p < 0.001) of these animals were significantly greater at T56 than at T0.ConclusionsIt was concluded that consumption of coffee husks was toxic to horses due to the high levels of caffeine present in their composition. Therefore, coffee husks pose a risk when used as bedding or as feed for horses.

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Section: Discussionmentioning

confidence: 99%

“…Furthermore, cattle have been shown to display signs of intoxication after one week of ingesting 3 kg, on average, of coffee husks used as bedding in their stalls [21]. Nevertheless, the addition of up to 1 kg of coffee husks with 0.97% caffeine in the diet of cattle did not produce clinical signs of intoxication [3,6]. …”

Section: Discussionmentioning

confidence: 99%

Equine poisoning by coffee husk (Coffea arabicaL.)

et al. 2012

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“…Choć doniesienia z Tajwanu [47] wskazują na nieco zwiększoną czę stość rozwoju pokrzywki we wspomnianych sytu acjach, to nie ma dostatecznych dowodów na zwią zek przyczynowoskutkowy pomiędzy pokrzywką a chorobami nowotworowymi. Natomiast gdy wy wiad chorego sugeruje chorobę nowotworową (np.…”

Section: Czy W Przypadku Pokrzywki Wywołanej Niespontanicznej Należyunclassified

The EAACI/GA2LEN/EDF/WAO Guideline for the definition, classification, diagnosis, and management of urticaria: the 2013 revision and update

Zuberbier¹,

Aberer²,

Asero³

et al. 2015

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“…The word ‘urticaria’ is derived from the Latin word urtica, which means ‘nettle’, which is a tooth-leaved plant covered with hairs that secret a stinging fluid that immediately affects the skin [1]. According to a previous study, more than 50% of patients continue to tolerate chronic urticaria 10 years after their initial diagnosis, and most of them need long-term treatment [2]. …”

Section: Introductionmentioning

confidence: 99%

Frequency and pattern of Chinese herbal medicine prescriptions for urticaria in Taiwan during 2009: analysis of the national health insurance database

Chien

Tseng

Hsu

et al. 2013

BMC Complement Altern Med

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BackgroundLarge-scale pharmaco-epidemiological studies of Chinese herbal medicine (CHM) for treatment of urticaria are few, even though clinical trials showed some CHM are effective. The purpose of this study was to explore the frequencies and patterns of CHM prescriptions for urticaria by analysing the population-based CHM database in Taiwan.MethodsThis study was linked to and processed through the complete traditional CHM database of the National Health Insurance Research Database in Taiwan during 2009. We calculated the frequencies and patterns of CHM prescriptions used for treatment of urticaria, of which the diagnosis was defined as the single ICD-9 Code of 708. Frequent itemset mining, as applied to data mining, was used to analyse co-prescription of CHM for patients with urticaria.ResultsThere were 37,386 subjects who visited traditional Chinese Medicine clinics for urticaria in Taiwan during 2009 and received a total of 95,765 CHM prescriptions. Subjects between 18 and 35 years of age comprised the largest number of those treated (32.76%). In addition, women used CHM for urticaria more frequently than men (female:male = 1.94:1). There was an average of 5.54 items prescribed in the form of either individual Chinese herbs or a formula in a single CHM prescription for urticaria. Bai-Xian-Pi (Dictamnus dasycarpus Turcz) was the most commonly prescribed single Chinese herb while Xiao-Feng San was the most commonly prescribed Chinese herbal formula. The most commonly prescribed CHM drug combination was Xiao-Feng San plus Bai-Xian-Pi while the most commonly prescribed triple drug combination was Xiao-Feng San, Bai-Xian-Pi, and Di-Fu Zi (Kochia scoparia).ConclusionsIn view of the popularity of CHM such as Xiao-Feng San prescribed for the wind-heat pattern of urticaria in this study, a large-scale, randomized clinical trial is warranted to research their efficacy and safety.

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Cancer Risk in Patients With Chronic Urticaria

Cited by 60 publications

References 28 publications

Equine poisoning by coffee husk (Coffea arabicaL.)

Equine poisoning by coffee husk (Coffea arabicaL.)

The EAACI/GA2LEN/EDF/WAO Guideline for the definition, classification, diagnosis, and management of urticaria: the 2013 revision and update

Frequency and pattern of Chinese herbal medicine prescriptions for urticaria in Taiwan during 2009: analysis of the national health insurance database

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