Cancer risk of immunosuppressants in manufacturing

Professional risks when carrying out cytoreductive surgery for peritoneal malignancy with hyperthermic intraperitoneal chemotherapy (HIPEC): A French multicentric survey

“…Chromosomal aberrations, micronuclei induction, DNA damage represent the most frequent abnormalities from occupational exposure [26]. Although limited, some publications demonstrate a relationship of occupational exposure to cytotoxic agents with cancer in health care workers [27,28]. Data are missing concerning the real impact to HIPEC exposure.…”

Modulation of Human Immune Response by Fungal Biocontrol Agents

“…As the structure of the fungal cell wall and the PAMPs exposed at the cell surface are genus-, species- and morphotype-dependent (Brodaczewska et al, 2015 ), detailed studies on modulation of the mammals immune system induced by biocontrol agent spores and mycotoxins is relevant to medicine and biotechnology. The compromised immune system may favor the development of opportunistic pathogens (Fishman, 2011 ) and even neoplastic diseases (Barle et al, 2014 ). The immunosuppressive molecules may comprise chemotherapy agents for autoimmunity and hypersensitivity reactions (Thell et al, 2014 ).…”