Cancer risks from head radiography procedures

Achuka, J. A.; Aweda, Moses Adebayo; Usikalu, M.R.

doi:10.1088/1755-1315/173/1/012038

Cited by 6 publications

(4 citation statements)

References 6 publications

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“…The results of this study are consistent with the results of our previous studies, which used X-rays from a skull radiography device as the LDR to induce a radioadaptation response [12]. Exposure doses of X-ray in head or skull radiography ranges from 3.01 to 19.12 mGy with a mean of 7.52 mGy [17], while this study used low-dose gamma rays of 50 mGy and 100 mGy. The increased priming irradiation doses up to 50 mGy and 100 mGy to induce radioadaptation response factually gives the similar results with dose of priming irradiation on skull radiography.…”

Section: Sod2supporting

confidence: 90%

Priming Low-Dose Gamma Irradiation Increases Cellular Radioadaptation Response through the Induction of Hsp70 and SOD2

2021

Atom Indo.

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Exposure to low-dose radiation has been demonstrated to stimulate increased cell protection when receiving subsequent challenge dose in what is known as radioadaptation response. Hsp70 and SOD, especially SOD2, are cytoprotectors against superoxide radicals generated by radiation exposure. This study aims to measure the expressions of Hsp70 and SOD2 in parotid salivary gland acinar cells as an indicator of radioadaptation response stimulated by low-dose gamma irradiation. The study used 24 male Rattus norvegicus that are divided into four groups: normal control, positive control, with 50-mGy priming irradiation, and with 100-mGy priming irradiation. The animals were immobilized without anesthetics with special tools designed especially for this study. Irradiation was carried out using a cobalt-60 (gamma ray) teletherapy unit (Philips XK-100) directed to the dorsa of the animals' heads. High-dose gamma irradiation (2 Gy) was administered 5 hours after priming irradiation. The expression of Hsp70 and SOD2 was measured through immunohistochemical technique on the parotid salivary gland acinar cells and observed using a light microscope with 1000× magnification. Data obtained was analyzed with one-way ANOVA test (α = 0.05). The results showed that Hsp70 and SOD2 expressions in the priming irradiation groups were higher than those in control groups. The conclusion of this study: priming irradiation with low-dose gamma radiation before challenge irradiation with high-dose gamma radiation increases the radioadaptation response of salivary gland acinar cells through induction of Hsp70 and SOD2.

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Section: Sod2supporting

confidence: 90%

Priming Low-Dose Gamma Irradiation Increases Cellular Radioadaptation Response through the Induction of Hsp70 and SOD2

2021

Atom Indo.

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“…Imaging modalities have been noted to deliver to patients in a wide range of doses [20,[22][23][24][25][26][27]. Same trend has been observed in this study; there is a large variation in the entrance surface dose (ESD) within the same hospital and from one center to others (Table 2).…”

Section: Discussionsupporting

confidence: 70%

Assessment of Patient Absorbed Radiation Dose during Hysterosalpingography: A Pilot Study in Southwest Nigeria

et al. 2019

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Background:Hysterosalpingography (HSG) is an indispensable tool for diagnosing infertility in females. The procedure exposes female reproductive organs to ionizing radiation as the genitals are irradiated during the process. Investigating patient absorbed dose during the procedures is essential for effective radiological protection of the patient.Objective: This study aims to investigate the radiation dose received by patient during HSG examination in the study environment in order to enhance optimization of procedures and the associated dose, thereby minimizing radiation risks.Material and Methods: The study was conducted in four tertiary healthcare institutions in Southwest Nigeria. Thermoluminescence dosimeter (TLD 100) was used to determine the Entrance Surface Dose (ESD) of 80 patients presented for HSG investigation. The corresponding effective dose, ovary, uterus and urinary bladder doses were evaluated using PCXMC software.Results: The means entrance surface dose (ESD) obtained from the four centers were 18.58±6.31 mGy, 15.18±2.27 mGy, 17.44±3.43 mGy and 34.24±11.98 mGy for SW1, SW2, SW3 and SW4 centers, respectively. The corresponding mean of effective doses were 1.54±0.63 mSv, 1.24±0.28 mSv, 1.41±0.30 mSv and 2.53±0.94 mSv for SW1, SW2, SW3 and SW4 centers, respectively. The resulting mean doses to the ovary, urinary bladder and uterus were also presented.Conclusion: The results obtained in general are comparable with international standards. It was, however, recommended that study centers with high doses should conduct dose audit in order to enhance patient safety.

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“…Radiographic equipment is widely in use globally. It has the highest frequency of imaging examinations as compared to other imaging modalities [1], [2], [3], [4], [5], [6]. Approximately 64% of all medical diagnostic examinations are from radiographic equipment [3].…”

Section: Introductionmentioning

confidence: 99%

“…Performance assessment of radiographic equipment cannot be over-emphasized. A little shift in any radiographic parameter has a significant impact on the patient absorbed dose [15], especially due to the incidence of cancer induction from radiographic examinations [6], [16]. It is therefore important that radiographic units be assessed before usage and periodically to ensure proper functioning.…”

Section: Introductionmentioning

confidence: 99%

Performance Characteristics of Radiographic equipment in Selected Healthcare Institutions in Southwest Nigeria

Ada

Rachael

Adebayo

et al. 2020

Open Access Maced J Med Sci

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BACKGROUND: Evaluation of radiographic equipment performance is the recommended strategy for the verification of factors used in radiodiagnosis. Sometimes, the performance of the equipment is compromised due to the lack of adoption of the appropriate procedures and/or techniques. AIM: The aim of this study was to determine the performance quality of the radiographic equipment in the study area in order to optimize the radiation dose delivered to the patients using these facilities and enhance their safety. METHODS: The performance characteristic of selected radiographic equipment was determined using MagicMax quality control kits and test object. Radiographic equipment in eight selected radiodiagnostic centers designated as C1-C8 was assessed. RESULTS: The results showed that all the radiography units in the studied centers passed the kVp reproducibility and mAs linearity tests with the exception of center C2. The kVp deviation for the centers varied between 2.0 and 7.7%, with the highest deviation in center C5 and lowest value in center C6. Center C7 has the highest deviation (–13%) of mAs, while the lowest value was obtained in center C6 (0%). The dose was lowest in center C1 and highest in center C3. The half-value layer, mAs, and filtration values had a stronger correlation with the incident air kerma dose compared to the other parameters. In addition, 50% of the equipment passed all the performance tests. CONCLUSION: The study revealed that the performance characteristics of radiographic equipment in the studied area require improvement. Periodic monitoring of the equipment performance is recommended for adoption and enforcement to enhance quality practices and radiation safety.

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Cancer risks from head radiography procedures

Cited by 6 publications

References 6 publications

Priming Low-Dose Gamma Irradiation Increases Cellular Radioadaptation Response through the Induction of Hsp70 and SOD2

Priming Low-Dose Gamma Irradiation Increases Cellular Radioadaptation Response through the Induction of Hsp70 and SOD2

Assessment of Patient Absorbed Radiation Dose during Hysterosalpingography: A Pilot Study in Southwest Nigeria

Performance Characteristics of Radiographic equipment in Selected Healthcare Institutions in Southwest Nigeria

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