Cancer Statistics, 2009

Abstract

Each year, the American Cancer Society estimates the number of new cancer cases and deaths expected in the United States in the current year and compiles the most recent data on cancer incidence, mortality, and survival based on incidence data from the National Cancer Institute, Centers for Disease Control and Prevention, and the North American Association of Central Cancer Registries and mortality data from the National Center for Health Statistics. Incidence and death rates are standardized by age to the 2000 United States standard million population. A total of 1,479,350 new cancer cases and 562,340 deaths from cancer are projected to occur in the United States in 2009. Overall cancer incidence rates decreased in the most recent time period in both men (1.8% per year from 2001 to 2005) and women (0.6% per year from 1998 to 2005), largely because of decreases in the three major cancer sites in men (lung, prostate, and colon and rectum [colorectum]) and in two major cancer sites in women (breast and colorectum). Overall cancer death rates decreased in men by 19.2% between 1990 and 2005, with decreases in lung (37%), prostate (24%), and colorectal (17%) cancer rates accounting for nearly 80% of the total decrease. Among women, overall cancer death rates between 1991 and 2005 decreased by 11.4%, with decreases in breast (37%) and colorectal (24%) cancer rates accounting for 60% of the total decrease. The reduction in the overall cancer death rates has resulted in the avoidance of about 650,000 deaths from cancer over the 15-year period. This report also examines cancer incidence, mortality, and survival by site, sex, race/ethnicity, education, geographic area, and calendar year. Although progress has been made in reducing incidence and mortality rates and improving survival, cancer still accounts for more deaths than heart disease in persons younger than 85 years of age. Further progress can be accelerated by applying existing cancer control knowledge across all segments of the population and by supporting new discoveries in cancer prevention, early detection, and treatment.

Phase II Efficacy and Pharmacogenomic Study of Selumetinib (AZD6244; ARRY-142886) in Iodine-131 Refractory Papillary Thyroid Carcinoma with or without Follicular Elements

“…Seven (18%) enrolled patients were not evaluable. This was due to PD prior to completion of 1 cycle (1), adverse effects of therapy (1), withdrawal of consent prior to completion of 1 cycle (4), and no disease evaluation per protocol (1). The patient with PD prior to cycle 1 received less than 1 cycle of therapy and then was referred to hospice without disease reevaluation.…”

“…New cases for 2009 are estimated at 37,200 (1). The prevalence is 410,404 and estimated deaths are 1,630 for 2009 (1). The most common type is papillary, comprising 70% to 80% of thyroid cancers.…”

“…The most common type is papillary, comprising 70% to 80% of thyroid cancers. The prognosis is extremely good for papillary thyroid cancer (PTC) with overall 10-year survival rates of 98% (1–3). Once thyroid cancer is locally advanced or metastatic and no longer amenable to surgery, however, expected survival declines significantly (4, 5).…”

A novel method for finding non-small cell lung cancer diagnosis biomarkers

“…Each year, around 1.5 million people were diagnosed with cancer and more than half of a million people died from cancer, which makes cancer a major public health problem in the United States as well as many other parts of the world [1,2]. The top five most common cancer-related deaths were due to lung, breast, prostate, colorectal and pancreatic cancer.…”

Physical Activity and Genitourinary Cancer Survivorship

“…Female breast cancer represents 27% of all new female cancers in developed countries: estimates project 192,370 new cases in the U.S. and 22,700 cases in Canada in 2009 (Canadian Cancer Society 2009;Jemal et al 2009). The lifetime risk of a woman being diagnosed with breast cancer is approximately one in eight in the United States (Jemal et al 2009) Worldwide, breast cancer is the most common cause of cancer death among women; the number of estimated deaths in 2002 was 410,712 (Ferlay et al 2004). In developed countries breast cancer is often the second leading cause of cancer death in women, following lung cancer (Canadian Cancer Society 2009;Jemal et al 2009;Office for National Statistics 2008).…”