Background
Colorectal cancer (CRC) is the second leading malignancy diagnosed among U.S. Latinos. Latinos in the U.S. represent a heterogeneous amalgam of subgroups varying in genetic background, culture, and socioeconomic status. Little is known about the frequency of CRC precursor lesions found at screening colonoscopy among Latino subgroups.
Aim
The aim was to determine the prevalence and distribution of histologically-confirmed adenomas found at screening colonoscopy among average-risk, asymptomatic U.S. Latinos according to their subgroup and socio-demographic background.
Methods
Cross-sectional analysis of pathological findings resulting from screening colonoscopy among average-risk, asymptomatic U.S. Latinos aged ≥ 50 in two prospective randomized controlled trials at an academic medical center.
Results
Among the 561 Latinos who completed screening colonoscopy, the two largest subgroups were Puerto Ricans and Dominicans. The findings among both subgroups were: adenomas 30.6%, proximal adenomas 23.5%, advanced adenomas 12.0%, and proximal advanced adenomas 8.9%. These rates are at least as high as those found at screening colonoscopy among U.S. whites. While Puerto Ricans were more likely than Dominicans to be born in the U.S., speak English, be acculturated, have a smoking history, and be obese, there were no significant differences in adenoma rates between these subgroups.
Conclusions
The prevalence of adenomas, advanced adenomas, and proximal neoplasia was high among both subgroups. These findings have implications for CRC screening and surveillance among the increasingly growing Latino population in the U.S.