Cancers du sein après radiothérapie : facteurs de risque et proposition de définition du sein chez la jeune fille prépubère comme organe à risque

Clinical and histological features of second breast cancers following radiotherapy for childhood and young adult malignancy

“…We have previously illustrated the risk of significant doses to the breast during abdominal irradiation, particularly in small children (less than 4 years or 1 m in height), and when an extensive field and/ or high doses are employed. 5 (3) For patients (n = 13) who had hypofractionated treatment, an equivalent dose was calculated using the linear quadratic model. 26 If the treatment field was asymmetric, the patient was included in the study only if the affected breast was estimated to have received 3 Gy or more.…”